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• W2022145953 abstract "Several protozoa have emerged as the major opportunistic infections and cause of death in patients with acquired immunodeficiency syndrome (AIDS). Pneumocystis carinii pneumonia is the leading cause of death in AIDS patients. Electron microscopy (EM) usually shows numerous trophozoites and cysts of Pneumocystis filling up the entire alveolar space, while only cysts are seen under the light microscope. The focal thickening of cyst wall of Pneumocystis, as demonstrated by EM and manifested as a “parentheses” shaped structure with silver stain, serves as a diagnostic marker for Pneumocystis. Freeze-fracture EM has demonstrated the intimate contact between Pneumocystis trophozoites and the type I pneumocytes, which may contribute to the alveolar-capillary block, leading to severe respiratory distress. However, EM is seldom needed for the diagnosis of this infection. Toxoplasma encephalitis, which is an unusual clinical manifestation in cases of toxoplasmosis reported previously, has become a common complication and one of the major causes of death in patients with AIDS. Because subclinical infection by Toxoplasma is common, serologic tests usually offer no definite answers as to whether the infection is acute or chronic, active or past. The small size and its non-specificity in both morphology and tissue affinity make light microscopic diagnosis of toxoplasmosis difficult. Only immunologic staining, such as immunoperoxidase and immunofluorescence, can help to achieve a definite positive identification of the organism. When special antibodies or facility for such staining is not available, EM is the final resort for identifying Toxoplasma by showing the apical complex with the characteristic sausageshaped rhoptries. Cryptosporidiosis, practically unknown before the AIDS outbreak, has become one of the most common intestinal protozoa in both immunocompromised and immunocompetent patients. The protracted and sometimes fatal course of cryptosporidiosis in immunocompromised patients can be explained by the presence of autoinfective oocysts (thin-walled oocysts), as detected by EM, and by recycling of first-generation schizonts observed experimentally. While diagnosis of cryptosporidiosis can be made by detection of oocysts in stools in most cases, EM is still the last resort for a definitive identification of Cryptosporidium species. While the incidence of isosporiasis is still low, it has been found more frequently in patients with AIDS than in the general population. The parasite, Isospora belli, being a coccidian as is the Cryptosporidium species, is similar to the latter in its life cycle and clinical manifestations. However, the morphology of its diagnostic stage, the oocyst, is quite different from Cryptosporidium and it is much larger than the latter. The oocyst of Isospora belli, usually containing one sporoblast, can be detected by light microscopy in stools. Microsporidiosis, having been known only recently, is also relatively common in immunocompromised patients, including four patients with AIDS. Although this protozoan can be detected by light microscopy and its polar granules, identified by the periodic acid-Schiff or methenamine silver stain, are characteristic, a definitive diagnosis of microsporidiosis still depends on EM." @default.
• W2022145953 created "2016-06-24" @default.
• W2022145953 creator A5071414886 @default.
• W2022145953 creator A5076873506 @default.
• W2022145953 date "1988-01-01" @default.
• W2022145953 modified "2023-10-18" @default.
• W2022145953 title "Protozoal infections in the acquired immunodeficiency syndrome" @default.
• W2022145953 cites W1146764538 @default.
• W2022145953 cites W1480374995 @default.
• W2022145953 cites W1515434500 @default.
• W2022145953 cites W1551782598 @default.
• W2022145953 cites W1555200014 @default.
• W2022145953 cites W1607927708 @default.
• W2022145953 cites W1646059134 @default.
• W2022145953 cites W1713613003 @default.
• W2022145953 cites W1825238515 @default.
• W2022145953 cites W1855742513 @default.
• W2022145953 cites W1869982146 @default.
• W2022145953 cites W1941902514 @default.
• W2022145953 cites W1949907270 @default.
• W2022145953 cites W1964432034 @default.
• W2022145953 cites W1966008931 @default.
• W2022145953 cites W1966877971 @default.
• W2022145953 cites W1969031921 @default.
• W2022145953 cites W1969785029 @default.
• W2022145953 cites W1969934346 @default.
• W2022145953 cites W1973082130 @default.
• W2022145953 cites W1976971672 @default.
• W2022145953 cites W1977683772 @default.
• W2022145953 cites W1981401182 @default.
• W2022145953 cites W1986574180 @default.
• W2022145953 cites W1991792257 @default.
• W2022145953 cites W1993189030 @default.
• W2022145953 cites W1994433019 @default.
• W2022145953 cites W1996730714 @default.
• W2022145953 cites W1996754743 @default.
• W2022145953 cites W2013499911 @default.
• W2022145953 cites W2023223458 @default.
• W2022145953 cites W2024110626 @default.
• W2022145953 cites W2028201578 @default.
• W2022145953 cites W2028320042 @default.
• W2022145953 cites W2029364823 @default.
• W2022145953 cites W2033814467 @default.
• W2022145953 cites W2034187488 @default.
• W2022145953 cites W2036073074 @default.
• W2022145953 cites W2039362004 @default.
• W2022145953 cites W2041815738 @default.
• W2022145953 cites W2050341293 @default.
• W2022145953 cites W2052258157 @default.
• W2022145953 cites W2052377231 @default.
• W2022145953 cites W2052810026 @default.
• W2022145953 cites W2056170961 @default.
• W2022145953 cites W2058736199 @default.
• W2022145953 cites W2062164907 @default.
• W2022145953 cites W2065224454 @default.
• W2022145953 cites W2067623909 @default.
• W2022145953 cites W2069095677 @default.
• W2022145953 cites W2069151065 @default.
• W2022145953 cites W2072131535 @default.
• W2022145953 cites W2075536729 @default.
• W2022145953 cites W2084395706 @default.
• W2022145953 cites W2089970888 @default.
• W2022145953 cites W2094199513 @default.
• W2022145953 cites W20948859 @default.
• W2022145953 cites W2102956619 @default.
• W2022145953 cites W2104676882 @default.
• W2022145953 cites W2110411605 @default.
• W2022145953 cites W2111627949 @default.
• W2022145953 cites W2118582462 @default.
• W2022145953 cites W2119760570 @default.
• W2022145953 cites W2120915049 @default.
• W2022145953 cites W2125803267 @default.
• W2022145953 cites W2137144194 @default.
• W2022145953 cites W2159521019 @default.
• W2022145953 cites W2171800021 @default.
• W2022145953 cites W2220837060 @default.
• W2022145953 cites W2317532242 @default.
• W2022145953 cites W2320388087 @default.
• W2022145953 cites W2327390162 @default.
• W2022145953 cites W2328628369 @default.
• W2022145953 cites W2329259771 @default.
• W2022145953 cites W2333215845 @default.
• W2022145953 cites W2334860476 @default.
• W2022145953 cites W2336627308 @default.
• W2022145953 cites W2337582164 @default.
• W2022145953 cites W2337859029 @default.
• W2022145953 cites W2338572106 @default.
• W2022145953 cites W2396461023 @default.
• W2022145953 cites W2411931823 @default.
• W2022145953 cites W3024876814 @default.
• W2022145953 cites W4243482908 @default.
• W2022145953 cites W64723363 @default.
• W2022145953 doi "https://doi.org/10.1002/jemt.1060080106" @default.
• W2022145953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3073196" @default.
• W2022145953 hasPublicationYear "1988" @default.
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