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- W2022149895 endingPage "242" @default.
- W2022149895 startingPage "235" @default.
- W2022149895 abstract "Over 250 species of bacteria have been detected in the vagina using genomic sequencing. Lactobacillus iners and L crispatus dominate in most women who have a clinically healthy status. Unfortunately, the abundance profiles can change dramatically with significant increases in pathogens associated with bacterial vaginosis (BV) and aerobic vaginitis (AV). The BV microbiota have at least 4 different abundance profiles, indicating this is a complex condition, yet one that is treated with essentially 2 antimicrobial agents which were never designed for eradicting these organisms in dense biofilms. Future studies will uncover which abundance profiles are particularly associated with a risk of preterm labor, and hopefully identify the mechanisms involved in the switch from healthy to a BV or AV state. The use of probiotic lactobacilli vaginally and orally has shown great promise in helping to restore and maintain a healthy vagina, and studies have shown that certain strains have the capacity to interfere with the inflammatory pathway leading to preterm delivery. There is enormous need for new diagnostic and therapeutic modalities, especially to save the lives of millions of babies in resource-disadvantaged countries." @default.
- W2022149895 created "2016-06-24" @default.
- W2022149895 creator A5004247993 @default.
- W2022149895 creator A5031693224 @default.
- W2022149895 creator A5038612099 @default.
- W2022149895 creator A5043064717 @default.
- W2022149895 date "2012-03-01" @default.
- W2022149895 modified "2023-09-24" @default.
- W2022149895 title "Importance of Vaginal Microbes in Reproductive Health" @default.
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- W2022149895 doi "https://doi.org/10.1177/1933719111418379" @default.