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- W2022151181 abstract "Effects of aging after epidural administration of 0.5% bupivacaine without epinephrine were studied in two groups of patients, between 20 and 55 yr old and older than 55 yr, respectively. All patients received 95 mg bupivacaine HCI. The onset of analgesia in caudad segments decreased with age and the upper level of analgesia increased with age. Effects of age on duration of anesthesia could not be demonstrated. The total plasma clearance of bupivacaine decreased and the terminal half-life increased with age. Age had no effect on the peak plasma concentrations and time to peak concentrations." @default.
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- W2022151181 date "1987-07-01" @default.
- W2022151181 modified "2023-10-13" @default.
- W2022151181 title "Epidural Anesthesia with Bupivacaine" @default.
- W2022151181 doi "https://doi.org/10.1213/00000539-198707000-00001" @default.
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