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- W2022152394 abstract "Abstract Objective —To evaluate the relationship between end-tidal partial pressure of CO 2 (ETCO 2 ) and PaCO 2 in isoflurane-anesthetized harp seals. Animals —Three 5-month-old 25- to 47-kg harp seals ( Phoca groenlandica ). Procedures —PaCO 2 was determined in serial arterial samples from isoflurane-anesthetized seals and compared with concomitant ETCO 2 measured with a side-stream microstream capnograph. Twenty-four paired samples were subjected to linear regression analysis and the Bland-Altman method for assessment of clinical suitability of the 2 methods (ie, PaCO 2 and ETCO 2 determinations). The influence of ventilation rate per minute (VR) on the ETCO 2 to PaCO 2 difference (P[ET-a] CO 2 ) was examined graphically. Results —The correlation coefficient between the 2 measurements was 0.94. The level of agreement between ETCO 2 and PaCO 2 varied considerably. Values of ETCO 2 obtained with a VR of < 5 underestimated PaCO 2 to a greater degree (mean bias, −4.01 mm Hg) and had wider limits of agreement of −13.10 to 5.07 mm Hg (−4.01 mm Hg ± 1.96 SD), compared with a VR of ≥ 5 (mean bias, −2.24 mm Hg; limits of agreement, −7.79 to 3.30 mm Hg). Conclusions and Clinical Relevance —These results indicate that a microstream sidestream capnograph provides a noninvasive, sufficiently accurate estimation of PaCO 2 with intermittent positive ventilation at a VR ≥ 5 in anesthetized harp seals." @default.
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- W2022152394 date "2006-07-01" @default.
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- W2022152394 title "Use of end-tidal partial pressure of carbon dioxide to predict arterial partial pressure of carbon dioxide in harp seals during isoflurane-induced anesthesia" @default.
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- W2022152394 doi "https://doi.org/10.2460/ajvr.67.7.1131" @default.
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