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- W2022152975 abstract "The separation of carrier-free 90Y from fission product 90Sr by solid supported solvent extraction chromatography was investigated using Teflon grain as solid support and a di-(2-ethylhexyl) phosphoric acid (D2EHPA) extraction agent as liquid phase. The optimum separation conditions are: (1) solid support using Dupont TF800 Teflon grains, (2) using 5% D2EHPA extraction agent as liquid phase, (3) setting the flow rate at 1 cm3/min, and (4) using a column diameter of 0.5 cm which was packed with 1 g treated Teflon. After loading 90Sr/90Y equilibrium solution, the loaded column was washed with 0.3 N hydrochloric acid to remove 90Sr species; subsequently, 8 N hydrochloric acid was used as an eluent to obtain a 90Y solution. Chemical yield was about 90%; radionuclide impurity of 90Sr in the final product was <10−6%. Consequently, the preparation of 1 mCi of 90Y was satisfactory for radiolabeling in medical applications. A radiotracer method using 85Sr and 88Y was also developed to investigate separation efficiency." @default.
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- W2022152975 date "1993-12-01" @default.
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- W2022152975 title "Preparation of carrier-free yttrium-90 for medical applications by solvent extraction chromatography" @default.
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