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- W2022155987 abstract "Heparin was linked covalently to Agarose by a reaction between aminoethyl Agarose and heparin in the presence of a water-soluble carbodiimide. Treatment of plasma with this product resulted in prolongation of coagulation and partial thromboplastin times. Assays of the treated plasma revealed that it was deficient in factors IX and XI. Elution of the heparin-linked Agarose with salt solutions yielded fractions containing these factors. Similar studies with serum indicated that heparin-cofactor is also bound to the immobilized heparin." @default.
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- W2022155987 date "1974-02-01" @default.
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- W2022155987 title "Preparation of heparin-linked Agarose and its interaction with plasma" @default.
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- W2022155987 doi "https://doi.org/10.1016/0049-3848(74)90089-9" @default.
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