Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022162227> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2022162227 endingPage "514" @default.
- W2022162227 startingPage "508" @default.
- W2022162227 abstract "The present study was designed to investigate the role of abnormalities in red blood cell sodium-potassium-chloride (Na-K-Cl) cotransport and Na+ pump as predictors of the pressor response to chronic oral Na+ loading in young whites and blacks. Subjects were healthy adults from 18 to 23 years of age and included normotensive whites (n = 24) and normotensive blacks (n = 35). Red blood cell transport studies were performed before Na+ loading. The Na+ load consisted of 10 g NaCl daily added to the usual diet. A sodium-sensitive response was defined as an increase of 5 mm Hg or more in mean arterial pressure after the Na+ load; a sodium-insensitive response was a less than 5 mm Hg increase in mean arterial pressure. A sodium-sensitive response occurred in 16% of whites and 57% of blacks. Black subjects have a significantly lower (p less than 0.005) maximal rate of furosemide-sensitive Na+ efflux and a higher Km for cellular Na+ (p less than 0.05) to activate Na-K-Cl cotransport than white subjects. Normotensive blacks with sodium-sensitive blood pressure response had a higher Km (14.4 +/- 6 mmol/l cell, n = 17, mean +/- SD) to activate the cotransport than sodium-insensitive blacks (9.9 +/- 3.7 mmol/l cell, n = 13, p less than 0.001). Normotensive whites had a significantly lower red blood cell Na+ content (p less than 0.05) and a higher maximal rate of cotransport (p less than 0.005) than young normotensive blacks.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2022162227 created "2016-06-24" @default.
- W2022162227 creator A5038780602 @default.
- W2022162227 creator A5042082896 @default.
- W2022162227 creator A5059947358 @default.
- W2022162227 date "1990-11-01" @default.
- W2022162227 modified "2023-09-23" @default.
- W2022162227 title "Red blood cell Na+ transport as a predictor of blood pressure response to Na+ load in young blacks and whites." @default.
- W2022162227 cites W1960130607 @default.
- W2022162227 cites W1971939173 @default.
- W2022162227 cites W1975850880 @default.
- W2022162227 cites W1978508573 @default.
- W2022162227 cites W1982499999 @default.
- W2022162227 cites W1983046349 @default.
- W2022162227 cites W1985983836 @default.
- W2022162227 cites W1993760518 @default.
- W2022162227 cites W2016112086 @default.
- W2022162227 cites W2018633989 @default.
- W2022162227 cites W2025550333 @default.
- W2022162227 cites W2059261098 @default.
- W2022162227 cites W2060377895 @default.
- W2022162227 cites W2113436936 @default.
- W2022162227 cites W2126109551 @default.
- W2022162227 cites W2126809650 @default.
- W2022162227 cites W2148076762 @default.
- W2022162227 cites W2199605993 @default.
- W2022162227 cites W2418224936 @default.
- W2022162227 cites W4252152729 @default.
- W2022162227 doi "https://doi.org/10.1161/01.hyp.16.5.508" @default.
- W2022162227 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2228151" @default.
- W2022162227 hasPublicationYear "1990" @default.
- W2022162227 type Work @default.
- W2022162227 sameAs 2022162227 @default.
- W2022162227 citedByCount "12" @default.
- W2022162227 crossrefType "journal-article" @default.
- W2022162227 hasAuthorship W2022162227A5038780602 @default.
- W2022162227 hasAuthorship W2022162227A5042082896 @default.
- W2022162227 hasAuthorship W2022162227A5059947358 @default.
- W2022162227 hasBestOaLocation W20221622271 @default.
- W2022162227 hasConcept C126322002 @default.
- W2022162227 hasConcept C134018914 @default.
- W2022162227 hasConcept C178790620 @default.
- W2022162227 hasConcept C185592680 @default.
- W2022162227 hasConcept C188053792 @default.
- W2022162227 hasConcept C2776557347 @default.
- W2022162227 hasConcept C2777955127 @default.
- W2022162227 hasConcept C517785266 @default.
- W2022162227 hasConcept C537181965 @default.
- W2022162227 hasConcept C71924100 @default.
- W2022162227 hasConcept C84393581 @default.
- W2022162227 hasConceptScore W2022162227C126322002 @default.
- W2022162227 hasConceptScore W2022162227C134018914 @default.
- W2022162227 hasConceptScore W2022162227C178790620 @default.
- W2022162227 hasConceptScore W2022162227C185592680 @default.
- W2022162227 hasConceptScore W2022162227C188053792 @default.
- W2022162227 hasConceptScore W2022162227C2776557347 @default.
- W2022162227 hasConceptScore W2022162227C2777955127 @default.
- W2022162227 hasConceptScore W2022162227C517785266 @default.
- W2022162227 hasConceptScore W2022162227C537181965 @default.
- W2022162227 hasConceptScore W2022162227C71924100 @default.
- W2022162227 hasConceptScore W2022162227C84393581 @default.
- W2022162227 hasIssue "5" @default.
- W2022162227 hasLocation W20221622271 @default.
- W2022162227 hasLocation W20221622272 @default.
- W2022162227 hasLocation W20221622273 @default.
- W2022162227 hasOpenAccess W2022162227 @default.
- W2022162227 hasPrimaryLocation W20221622271 @default.
- W2022162227 hasRelatedWork W179244222 @default.
- W2022162227 hasRelatedWork W1968941138 @default.
- W2022162227 hasRelatedWork W1994072104 @default.
- W2022162227 hasRelatedWork W2000398538 @default.
- W2022162227 hasRelatedWork W2004379323 @default.
- W2022162227 hasRelatedWork W2022162227 @default.
- W2022162227 hasRelatedWork W2045622995 @default.
- W2022162227 hasRelatedWork W2059172470 @default.
- W2022162227 hasRelatedWork W2414103222 @default.
- W2022162227 hasRelatedWork W2748952813 @default.
- W2022162227 hasVolume "16" @default.
- W2022162227 isParatext "false" @default.
- W2022162227 isRetracted "false" @default.
- W2022162227 magId "2022162227" @default.
- W2022162227 workType "article" @default.