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- W2022165630 abstract "The value of a depot cobalamin preparation Betolvex (cyanocobalamin-tannin complex suspended in a sesame-oil aluminum-monostearate gel) in the maintenance therapy of pernicious anaemia was investigated in 120 patients followed up for between 8 and 15 years. Complete haematological remission was maintained in all patients, and none developed B12 neuropathy after the start of treatment. No side-effects were observed. The mean values of S-cobalamin were above the reference limits when 1 mg cobalamin was given every 2 months, and high within the reference limits when given at 3 monthly intervals. The cobalamin content in the liver tissue in 2 patients who had received 1 mg cobalamin every 3 months for 6 years revealed normal values. Thus, 1 mg of the depot cobalamin preparation given at intervals of 3 months should provide adequate maintenance therapy in pernicious anaemia." @default.
- W2022165630 created "2016-06-24" @default.
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- W2022165630 date "2009-04-24" @default.
- W2022165630 modified "2023-09-26" @default.
- W2022165630 title "Long Term Therapy of Pernicious Anaemia with the Depot Cobalamin Preparation Betolvex®" @default.
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- W2022165630 doi "https://doi.org/10.1111/j.1600-0609.1983.tb02137.x" @default.
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