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- W2022168927 abstract "Acute and chronic studies were performed in the canine model to evaluate a new topical hemostatic agent in terms of initial hemostatic capability and tissue/material interaction during the healing process. IP760, a porous amylose succinate material, was applied to large splenic surface wounds in six acute and twelve chronic animals. Microfibrillar collagen (Avitene) was used in twelve chronic animals for comparison. While the hemostatic capabilities of the two agents were comparable, marked differences were noted in the healing response. In the IP760-treated wound sites the acute inflammatory response, granulation tissue infiltration with fibrosis and healing occurred earlier and in a more homogeneous manner than in the Avitene-treated wound sites. Healing of the IP760-treated wounds occurred concomitantly with the development of granulation tissue and fibrosis and the rapid resorption of the IP760." @default.
- W2022168927 created "2016-06-24" @default.
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- W2022168927 date "1982-01-01" @default.
- W2022168927 modified "2023-09-25" @default.
- W2022168927 title "Hemostatic and healing studies of sodium amylose succinate (IP760)" @default.
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- W2022168927 doi "https://doi.org/10.1002/jbm.820160108" @default.
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