FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022176307> ?p ?o ?g. }

• W2022176307 endingPage "S51" @default.
• W2022176307 startingPage "S47" @default.
• W2022176307 abstract "Family and twin studies of developmental dyslexia have consistently shown that there is a significant heritable component for this disorder. However, any genetic basis for the trait is likely to be complex, involving reduced penetrance, phenocopy, heterogeneity and oligogenic inheritance. This complexity results in reduced power for traditional parametric linkage analysis, where specification of the correct genetic model is important. One strategy is to focus on large multigenerational pedigrees with severe phenotypes and/or apparent simple Mendelian inheritance, as has been success-fully demonstrated for speech and language impairment. This approach is limited by the scarcity of such families. An alternative which has recently become feasible due to the development of high-throughput genotyping techniques is the analysis of large numbers of sib-pairs using allelesharing methodology. This paper outlines our strategy for conducting a systematic genome-wide search for genes involved in dyslexia in a large number of affected sib-pair familites from the UK. We use a series of psychometric tests to obtain different quantitative measures of reading deficit, which should correlate with different components of the dyslexia phenotype, such as phonological awareness and orthographic coding ability. This enables us to use QTL (quantitative trait locus) mapping as a powerful tool for localising genes which may contribute to reading and spelling disability." @default.
• W2022176307 created "2016-06-24" @default.
• W2022176307 creator A5031648152 @default.
• W2022176307 creator A5038938677 @default.
• W2022176307 creator A5082524516 @default.
• W2022176307 date "1999-09-01" @default.
• W2022176307 modified "2023-09-25" @default.
• W2022176307 title "A genome-wide search strategy for identifying quantitative trait loci involved in reading and spelling disability (developmental dyslexia)" @default.
• W2022176307 cites W1569189507 @default.
• W2022176307 cites W1965265115 @default.
• W2022176307 cites W1977104259 @default.
• W2022176307 cites W1982206156 @default.
• W2022176307 cites W1992842121 @default.
• W2022176307 cites W1994571321 @default.
• W2022176307 cites W1999377301 @default.
• W2022176307 cites W2003035537 @default.
• W2022176307 cites W2018210620 @default.
• W2022176307 cites W2021991929 @default.
• W2022176307 cites W2036284697 @default.
• W2022176307 cites W2042831569 @default.
• W2022176307 cites W2051225102 @default.
• W2022176307 cites W2069035587 @default.
• W2022176307 cites W2085837439 @default.
• W2022176307 cites W2086188454 @default.
• W2022176307 cites W2088988435 @default.
• W2022176307 cites W2090893963 @default.
• W2022176307 cites W2093214731 @default.
• W2022176307 cites W2100714054 @default.
• W2022176307 cites W2123466824 @default.
• W2022176307 cites W2141006860 @default.
• W2022176307 cites W2160729986 @default.
• W2022176307 cites W2404559228 @default.
• W2022176307 cites W4234074897 @default.
• W2022176307 doi "https://doi.org/10.1007/pl00010694" @default.
• W2022176307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10638370" @default.
• W2022176307 hasPublicationYear "1999" @default.
• W2022176307 type Work @default.
• W2022176307 sameAs 2022176307 @default.
• W2022176307 citedByCount "22" @default.
• W2022176307 countsByYear W20221763072012 @default.
• W2022176307 countsByYear W20221763072013 @default.
• W2022176307 countsByYear W20221763072016 @default.
• W2022176307 countsByYear W20221763072017 @default.
• W2022176307 crossrefType "journal-article" @default.
• W2022176307 hasAuthorship W2022176307A5031648152 @default.
• W2022176307 hasAuthorship W2022176307A5038938677 @default.
• W2022176307 hasAuthorship W2022176307A5082524516 @default.
• W2022176307 hasBestOaLocation W20221763072 @default.
• W2022176307 hasConcept C104317684 @default.
• W2022176307 hasConcept C106208931 @default.
• W2022176307 hasConcept C106934330 @default.
• W2022176307 hasConcept C135763542 @default.
• W2022176307 hasConcept C138496976 @default.
• W2022176307 hasConcept C138885662 @default.
• W2022176307 hasConcept C153209595 @default.
• W2022176307 hasConcept C15744967 @default.
• W2022176307 hasConcept C175783326 @default.
• W2022176307 hasConcept C180747234 @default.
• W2022176307 hasConcept C199360897 @default.
• W2022176307 hasConcept C41008148 @default.
• W2022176307 hasConcept C41895202 @default.
• W2022176307 hasConcept C506058694 @default.
• W2022176307 hasConcept C54355233 @default.
• W2022176307 hasConcept C554936623 @default.
• W2022176307 hasConcept C81941488 @default.
• W2022176307 hasConcept C86803240 @default.
• W2022176307 hasConceptScore W2022176307C104317684 @default.
• W2022176307 hasConceptScore W2022176307C106208931 @default.
• W2022176307 hasConceptScore W2022176307C106934330 @default.
• W2022176307 hasConceptScore W2022176307C135763542 @default.
• W2022176307 hasConceptScore W2022176307C138496976 @default.
• W2022176307 hasConceptScore W2022176307C138885662 @default.
• W2022176307 hasConceptScore W2022176307C153209595 @default.
• W2022176307 hasConceptScore W2022176307C15744967 @default.
• W2022176307 hasConceptScore W2022176307C175783326 @default.
• W2022176307 hasConceptScore W2022176307C180747234 @default.
• W2022176307 hasConceptScore W2022176307C199360897 @default.
• W2022176307 hasConceptScore W2022176307C41008148 @default.
• W2022176307 hasConceptScore W2022176307C41895202 @default.
• W2022176307 hasConceptScore W2022176307C506058694 @default.
• W2022176307 hasConceptScore W2022176307C54355233 @default.
• W2022176307 hasConceptScore W2022176307C554936623 @default.
• W2022176307 hasConceptScore W2022176307C81941488 @default.
• W2022176307 hasConceptScore W2022176307C86803240 @default.
• W2022176307 hasIssue "S3" @default.
• W2022176307 hasLocation W20221763071 @default.
• W2022176307 hasLocation W20221763072 @default.
• W2022176307 hasLocation W20221763073 @default.
• W2022176307 hasOpenAccess W2022176307 @default.
• W2022176307 hasPrimaryLocation W20221763071 @default.
• W2022176307 hasRelatedWork W2002128513 @default.
• W2022176307 hasRelatedWork W2022953845 @default.
• W2022176307 hasRelatedWork W2057739827 @default.
• W2022176307 hasRelatedWork W2099281994 @default.
• W2022176307 hasRelatedWork W2159975710 @default.
• W2022176307 hasRelatedWork W2483883060 @default.
• W2022176307 hasRelatedWork W4231021975 @default.
• W2022176307 hasRelatedWork W4311569799 @default.

• next