FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022182117> ?p ?o ?g. }

• W2022182117 endingPage "922" @default.
• W2022182117 startingPage "916" @default.
• W2022182117 abstract "This clinical trial, which was composed of 1,031 adults undergoing cardiac operations, compared the efficacy of a single dose of 1 g of ceftriaxone with a 48-our regimen consisting of flucloxacillin and gentamicin. There was no significant difference (p = 0.89) in the overall incidence of major infections: 30 of 515 patients (5.8%; 95% confidence interval, 5.4% to 6.2%) taking ceftriaxone and 29 of 516 patients (5.6%; 95% confidence interval, 5.2% to 6.0%) taking flucloxacillin and gentamicin. Subgroup analyses, with a lower statistical power, failed to show a significant difference between patients who received ceftriaxone and those who received flucloxacillin/gentamicin: major sternal wound infections arose in 2.7% of the patients taking ceftriaxone versus 1.6% in those on the 48-hour regimen (p = 0.20) and major limb wound infections arose in 4.2% and 5.4%, respectively (p = 0.44). Single-dose prophylaxis was associated with fewer intravenous administrations (864 doses versus 9,570 doses) and cost less (A$17,248 versus A$78,510). Although the regimen that included gentamicin was associated with the greatest biochemical impairment of renal function, the overall toxicity for both groups was low. We conclude that a single dose of ceftriaxone provided cost-efficient prophylaxis for adults undergoing cardiac operations when compared with a 48-hour regimen of gentamicin and flucloxacillin. The general principle revealed by our data is that the short-term administration of an appropriate antibiotic regimen represents optimal prophylaxis for patients undergoing cardiac procedures." @default.
• W2022182117 created "2016-06-24" @default.
• W2022182117 creator A5016765243 @default.
• W2022182117 creator A5034734755 @default.
• W2022182117 creator A5056962781 @default.
• W2022182117 creator A5064591801 @default.
• W2022182117 creator A5072276712 @default.
• W2022182117 creator A5073406579 @default.
• W2022182117 creator A5075748375 @default.
• W2022182117 creator A5083174288 @default.
• W2022182117 date "1993-10-01" @default.
• W2022182117 modified "2023-10-06" @default.
• W2022182117 title "Antibiotic prophylaxis in cardiac operations" @default.
• W2022182117 cites W1532759464 @default.
• W2022182117 cites W1536565168 @default.
• W2022182117 cites W1963771080 @default.
• W2022182117 cites W1984285285 @default.
• W2022182117 cites W1985475680 @default.
• W2022182117 cites W2002798252 @default.
• W2022182117 cites W2023626522 @default.
• W2022182117 cites W2028227799 @default.
• W2022182117 cites W2033331961 @default.
• W2022182117 cites W2040906358 @default.
• W2022182117 cites W2042150802 @default.
• W2022182117 cites W2048226452 @default.
• W2022182117 cites W2070051498 @default.
• W2022182117 cites W2087576469 @default.
• W2022182117 cites W2097968519 @default.
• W2022182117 cites W2104312285 @default.
• W2022182117 cites W2131148629 @default.
• W2022182117 cites W2141289234 @default.
• W2022182117 cites W2143429021 @default.
• W2022182117 cites W2147784727 @default.
• W2022182117 cites W2409537160 @default.
• W2022182117 doi "https://doi.org/10.1016/0003-4975(93)90355-l" @default.
• W2022182117 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8215669" @default.
• W2022182117 hasPublicationYear "1993" @default.
• W2022182117 type Work @default.
• W2022182117 sameAs 2022182117 @default.
• W2022182117 citedByCount "37" @default.
• W2022182117 countsByYear W20221821172015 @default.
• W2022182117 countsByYear W20221821172016 @default.
• W2022182117 countsByYear W20221821172020 @default.
• W2022182117 countsByYear W20221821172023 @default.
• W2022182117 crossrefType "journal-article" @default.
• W2022182117 hasAuthorship W2022182117A5016765243 @default.
• W2022182117 hasAuthorship W2022182117A5034734755 @default.
• W2022182117 hasAuthorship W2022182117A5056962781 @default.
• W2022182117 hasAuthorship W2022182117A5064591801 @default.
• W2022182117 hasAuthorship W2022182117A5072276712 @default.
• W2022182117 hasAuthorship W2022182117A5073406579 @default.
• W2022182117 hasAuthorship W2022182117A5075748375 @default.
• W2022182117 hasAuthorship W2022182117A5083174288 @default.
• W2022182117 hasConcept C120665830 @default.
• W2022182117 hasConcept C121332964 @default.
• W2022182117 hasConcept C126322002 @default.
• W2022182117 hasConcept C141071460 @default.
• W2022182117 hasConcept C2775832221 @default.
• W2022182117 hasConcept C2776520383 @default.
• W2022182117 hasConcept C2778355172 @default.
• W2022182117 hasConcept C2778602436 @default.
• W2022182117 hasConcept C2779489039 @default.
• W2022182117 hasConcept C2781413609 @default.
• W2022182117 hasConcept C42219234 @default.
• W2022182117 hasConcept C44249647 @default.
• W2022182117 hasConcept C501593827 @default.
• W2022182117 hasConcept C523546767 @default.
• W2022182117 hasConcept C54355233 @default.
• W2022182117 hasConcept C61511704 @default.
• W2022182117 hasConcept C71924100 @default.
• W2022182117 hasConcept C86803240 @default.
• W2022182117 hasConcept C89423630 @default.
• W2022182117 hasConceptScore W2022182117C120665830 @default.
• W2022182117 hasConceptScore W2022182117C121332964 @default.
• W2022182117 hasConceptScore W2022182117C126322002 @default.
• W2022182117 hasConceptScore W2022182117C141071460 @default.
• W2022182117 hasConceptScore W2022182117C2775832221 @default.
• W2022182117 hasConceptScore W2022182117C2776520383 @default.
• W2022182117 hasConceptScore W2022182117C2778355172 @default.
• W2022182117 hasConceptScore W2022182117C2778602436 @default.
• W2022182117 hasConceptScore W2022182117C2779489039 @default.
• W2022182117 hasConceptScore W2022182117C2781413609 @default.
• W2022182117 hasConceptScore W2022182117C42219234 @default.
• W2022182117 hasConceptScore W2022182117C44249647 @default.
• W2022182117 hasConceptScore W2022182117C501593827 @default.
• W2022182117 hasConceptScore W2022182117C523546767 @default.
• W2022182117 hasConceptScore W2022182117C54355233 @default.
• W2022182117 hasConceptScore W2022182117C61511704 @default.
• W2022182117 hasConceptScore W2022182117C71924100 @default.
• W2022182117 hasConceptScore W2022182117C86803240 @default.
• W2022182117 hasConceptScore W2022182117C89423630 @default.
• W2022182117 hasIssue "4" @default.
• W2022182117 hasLocation W20221821171 @default.
• W2022182117 hasLocation W20221821172 @default.
• W2022182117 hasOpenAccess W2022182117 @default.
• W2022182117 hasPrimaryLocation W20221821171 @default.
• W2022182117 hasRelatedWork W145269271 @default.
• W2022182117 hasRelatedWork W1986761366 @default.

• next