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• W2022182148 abstract "A positive sentinel lymph node (SLN) biopsy is an indication for completion lymph node dissection (CLND) in malignant melanoma; however, most CLNDs are negative. We hypothesized SLN metastatic size of < or =2 mm would predict CLND status and prognosis.We evaluated 80 consecutive patients undergoing CLND for positive SLNs over a 10-year period. Incidence of positive nonsentinel nodes and survival were compared for patients with SLN metastases < or =2 mm and >2 mm.Of 504 patients undergoing SLN biopsy, 49 patients had SLN deposits < or =2 mm and a 6% incidence of positive CLNDs. Five-year survival was 85%, essentially the same as negative SLN biopsies. In contrast, 31 had SLN metastases >2 mm, a 45% incidence of addition disease at CLND, and 5-year survival of 47% (P < .0001).An SLN metastatic cut point of 2 mm is an efficient predictor of CLND status and survival in malignant melanoma." @default.
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• W2022182148 date "2006-12-01" @default.
• W2022182148 modified "2023-09-24" @default.
• W2022182148 title "Size of sentinel node metastases predicts other nodal disease and survival in malignant melanoma" @default.
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• W2022182148 doi "https://doi.org/10.1016/j.amjsurg.2006.08.062" @default.
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