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- W2022188938 abstract "In two-component signaling systems, phosphorylated response regulators (RRs) are often dephosphorylated by their partner kinases in order to control the in vivo concentration of phospho-RR (RR∼P). This activity is easily demonstrated in vitro, but these experiments have typically used very high concentrations of the histidine kinase (HK) compared to the RR∼P. Many two-component systems exhibit exquisite control over the ratio of HK to RR in vivo. The question thus arises as to whether the phosphatase activity of HKs is significant in vivo. This topic will be explored in the present review." @default.
- W2022188938 created "2016-06-24" @default.
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- W2022188938 date "2010-04-01" @default.
- W2022188938 modified "2023-09-26" @default.
- W2022188938 title "How important is the phosphatase activity of sensor kinases?" @default.
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- W2022188938 doi "https://doi.org/10.1016/j.mib.2010.01.013" @default.
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