Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022189400> ?p ?o ?g. }
- W2022189400 endingPage "1029" @default.
- W2022189400 startingPage "1021" @default.
- W2022189400 abstract "Alcohol-related liver disease is a major cause of morbidity and mortality in the United States. Alcoholic liver disease encompasses a clinicohistological spectrum, including fatty liver, alcoholic hepatitis, and alcoholic cirrhosis. Fatty liver is a benign and reversible condition, but progression to alcoholic hepatitis and cirrhosis is life-threatening. Alcoholic hepatitis is diagnosed predominantly on clinical history, physical examination, and laboratory testing, although liver biopsy is often necessary to secure the diagnosis. The major focus of management is abstinence from alcohol, supportive care, treatment of complications of infection and portal hypertension, and maintenance of positive nitrogen balance through nutritional support. Corticosteroid therapy is controversial but should be considered in patients with a discriminant function greater than 32 and/or presence of spontaneous hepatic encephalopathy in the absence of infection, gastrointestinal bleeding, and renal failure. The only curative therapy for advanced alcoholic cirrhosis is liver transplantation. Several recent advances in understanding the pathogenesis of alcoholic liver disease may lead to novel future treatment approaches, including inhibition of tumor necrosis factor a, antioxidant therapy, stimulation of liver regeneration, and stimulation of collagen degradation." @default.
- W2022189400 created "2016-06-24" @default.
- W2022189400 creator A5000664757 @default.
- W2022189400 creator A5004470985 @default.
- W2022189400 creator A5048615239 @default.
- W2022189400 date "2001-10-01" @default.
- W2022189400 modified "2023-10-14" @default.
- W2022189400 title "Pathogenesis, Diagnosis, and Treatment of Alcoholic Liver Disease" @default.
- W2022189400 cites W1514796040 @default.
- W2022189400 cites W1533012305 @default.
- W2022189400 cites W1539538252 @default.
- W2022189400 cites W1695702879 @default.
- W2022189400 cites W1889183644 @default.
- W2022189400 cites W1965057934 @default.
- W2022189400 cites W1966654614 @default.
- W2022189400 cites W1974316968 @default.
- W2022189400 cites W1978447560 @default.
- W2022189400 cites W1979454312 @default.
- W2022189400 cites W1982358260 @default.
- W2022189400 cites W1987296974 @default.
- W2022189400 cites W1994196181 @default.
- W2022189400 cites W1997519816 @default.
- W2022189400 cites W2002216094 @default.
- W2022189400 cites W2004317356 @default.
- W2022189400 cites W2006187783 @default.
- W2022189400 cites W2013134500 @default.
- W2022189400 cites W2013412146 @default.
- W2022189400 cites W2018033081 @default.
- W2022189400 cites W2018630692 @default.
- W2022189400 cites W2028821776 @default.
- W2022189400 cites W2032616894 @default.
- W2022189400 cites W2033054063 @default.
- W2022189400 cites W2033973103 @default.
- W2022189400 cites W2034320774 @default.
- W2022189400 cites W2035199617 @default.
- W2022189400 cites W2036339298 @default.
- W2022189400 cites W2042324298 @default.
- W2022189400 cites W2044191097 @default.
- W2022189400 cites W2047732107 @default.
- W2022189400 cites W2050377794 @default.
- W2022189400 cites W2054200872 @default.
- W2022189400 cites W2054511859 @default.
- W2022189400 cites W2057594695 @default.
- W2022189400 cites W2060624748 @default.
- W2022189400 cites W2060729546 @default.
- W2022189400 cites W2062295765 @default.
- W2022189400 cites W2065157394 @default.
- W2022189400 cites W2067767440 @default.
- W2022189400 cites W2083412018 @default.
- W2022189400 cites W2084815601 @default.
- W2022189400 cites W2091440199 @default.
- W2022189400 cites W2092106039 @default.
- W2022189400 cites W2101028576 @default.
- W2022189400 cites W2102866245 @default.
- W2022189400 cites W2104277391 @default.
- W2022189400 cites W2115734865 @default.
- W2022189400 cites W2139230772 @default.
- W2022189400 cites W2139825247 @default.
- W2022189400 cites W2142511784 @default.
- W2022189400 cites W2149449252 @default.
- W2022189400 cites W2150445215 @default.
- W2022189400 cites W2154092306 @default.
- W2022189400 cites W2154157434 @default.
- W2022189400 cites W2155917817 @default.
- W2022189400 cites W2156153913 @default.
- W2022189400 cites W2160939065 @default.
- W2022189400 cites W2161261662 @default.
- W2022189400 cites W2183591749 @default.
- W2022189400 cites W2325156742 @default.
- W2022189400 cites W2333824726 @default.
- W2022189400 cites W2336449142 @default.
- W2022189400 cites W2942434766 @default.
- W2022189400 cites W2943618816 @default.
- W2022189400 cites W59176708 @default.
- W2022189400 cites W2093030719 @default.
- W2022189400 doi "https://doi.org/10.4065/76.10.1021" @default.
- W2022189400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11605686" @default.
- W2022189400 hasPublicationYear "2001" @default.
- W2022189400 type Work @default.
- W2022189400 sameAs 2022189400 @default.
- W2022189400 citedByCount "133" @default.
- W2022189400 countsByYear W20221894002012 @default.
- W2022189400 countsByYear W20221894002013 @default.
- W2022189400 countsByYear W20221894002014 @default.
- W2022189400 countsByYear W20221894002015 @default.
- W2022189400 countsByYear W20221894002016 @default.
- W2022189400 countsByYear W20221894002017 @default.
- W2022189400 countsByYear W20221894002018 @default.
- W2022189400 countsByYear W20221894002019 @default.
- W2022189400 countsByYear W20221894002020 @default.
- W2022189400 countsByYear W20221894002021 @default.
- W2022189400 countsByYear W20221894002022 @default.
- W2022189400 countsByYear W20221894002023 @default.
- W2022189400 crossrefType "journal-article" @default.
- W2022189400 hasAuthorship W2022189400A5000664757 @default.
- W2022189400 hasAuthorship W2022189400A5004470985 @default.
- W2022189400 hasAuthorship W2022189400A5048615239 @default.
- W2022189400 hasBestOaLocation W20221894001 @default.