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- W2022203345 abstract "We describe studies concerning the ability of a nuclear dinucleoside triphosphatase to act as a decapping enzyme in RNA catabolism. The enzymatic release of GMP from the Gp3A moiety was determined in the capped RNA model compounds GP3A3′pA, Gp3A3′pA-isoprop and Gp3A2′pA in isolated rat liver nuclei; i.e., in the environment in which the dinucleoside triphosphatase operates in vivo. The Gp3A cap moiety is hydrolyzed in (3′-5′) linked nucleotides only, whereas an extension of the Gp3A in the 2′-direction prevents the nuclear triphosphatase to operate." @default.
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- W2022203345 date "1984-01-23" @default.
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- W2022203345 title "Catabolism of capped (3′-5′)- and (2′-5′)-adenylates in rat liver nuclei" @default.
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- W2022203345 doi "https://doi.org/10.1016/0014-5793(84)80044-7" @default.
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