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- W2022204465 abstract "Carbonic anhydrase activity was studied in the blood of fifteen species of mammals ranging in body weight from about 0·006 to 600 kg. In general, the red cells of the small animals were found to have a higher enzyme activity than those of the larger species. The relationship, when considered in terms of the requirements for CO2 transport, indicates that the enzyme is present in excess of the requirements even for the smaller animals with high metabolic rates. It is instead suggested that the enzyme could influence oxygen dissociation of hemoglobin due to a combination of the following factors: (a) small animals with high metabolic rates have the largest CO2 production and the largest amount of red cell carbonic anhydrase. (b) Small species also have more acid sensitive hemoglobins (marked Bohr effect). Therefore, a rapid hydration of CO2, forming carbonic acid, might allow the Bohr effect in the small animals to cause the delivery of more oxygen to the tissues during the short time the red cells remain in the capillaries." @default.
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- W2022204465 date "1960-01-01" @default.
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- W2022204465 title "A comparison of blood carbonic anhydrase of various mammals" @default.
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