Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022205904> ?p ?o ?g. }
- W2022205904 endingPage "142" @default.
- W2022205904 startingPage "135" @default.
- W2022205904 abstract "The oxygen dependence of a first generation amperometric biosensor was investigated in vitro and in vivo by monitoring its glucose response as a function of solution pO2. The biosensor was a glucose oxidase (GOx) modified poly(o-phenylenediamine) coated Pt cylinder electrode (Pt/PPD/GOx) that has been designed for neurochemical analysis in vivo. Two types of oxygen probes were used: a self-calibrating commercial macroelectrode in vitro; and a carbon paste microelectrode in vivo. Calibrations in vitro showed that oxygen interference in the operation of Pt/PPD/GOx electrodes was minimal for concentrations of glucose (∼0.5 mM) and oxygen (∼50 μM) found in brain ECF. This observation was confirmed by simultaneous monitoring in vivo of brain glucose and oxygen in the awake rat. However, at levels of glucose normally found in peripheral tissues (∼5 mM), the oxygen dependence was severe. We conclude that the oxygen sensitivity of Pt/PPD/GOx biosensors does not preclude their reliable use in media containing low glucose levels, such as brain ECF." @default.
- W2022205904 created "2016-06-24" @default.
- W2022205904 creator A5010532635 @default.
- W2022205904 creator A5047255137 @default.
- W2022205904 creator A5072162477 @default.
- W2022205904 date "2002-09-01" @default.
- W2022205904 modified "2023-10-15" @default.
- W2022205904 title "Characterization in vitro and in vivo of the oxygen dependence of an enzyme/polymer biosensor for monitoring brain glucose" @default.
- W2022205904 cites W1584617952 @default.
- W2022205904 cites W1964975785 @default.
- W2022205904 cites W1970041475 @default.
- W2022205904 cites W1971988863 @default.
- W2022205904 cites W1976989422 @default.
- W2022205904 cites W1984139105 @default.
- W2022205904 cites W1993016494 @default.
- W2022205904 cites W1998106414 @default.
- W2022205904 cites W2003281596 @default.
- W2022205904 cites W2004438550 @default.
- W2022205904 cites W2005504986 @default.
- W2022205904 cites W2009383681 @default.
- W2022205904 cites W2011922821 @default.
- W2022205904 cites W2012389161 @default.
- W2022205904 cites W2014933742 @default.
- W2022205904 cites W2015139372 @default.
- W2022205904 cites W2016380458 @default.
- W2022205904 cites W2026549110 @default.
- W2022205904 cites W2031073030 @default.
- W2022205904 cites W2034997737 @default.
- W2022205904 cites W2036710261 @default.
- W2022205904 cites W2043152840 @default.
- W2022205904 cites W2043281666 @default.
- W2022205904 cites W2043988282 @default.
- W2022205904 cites W2049407418 @default.
- W2022205904 cites W2049855163 @default.
- W2022205904 cites W2062908486 @default.
- W2022205904 cites W2071545981 @default.
- W2022205904 cites W2081755645 @default.
- W2022205904 cites W2082184675 @default.
- W2022205904 cites W2082254615 @default.
- W2022205904 cites W2082731488 @default.
- W2022205904 cites W2084366853 @default.
- W2022205904 cites W2085655863 @default.
- W2022205904 cites W2089771894 @default.
- W2022205904 cites W2091449195 @default.
- W2022205904 cites W2092884623 @default.
- W2022205904 cites W2094405050 @default.
- W2022205904 cites W2094850942 @default.
- W2022205904 cites W2104517032 @default.
- W2022205904 cites W2115876736 @default.
- W2022205904 cites W2127734905 @default.
- W2022205904 cites W4238778103 @default.
- W2022205904 cites W4246845864 @default.
- W2022205904 doi "https://doi.org/10.1016/s0165-0270(02)00170-x" @default.
- W2022205904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12323417" @default.
- W2022205904 hasPublicationYear "2002" @default.
- W2022205904 type Work @default.
- W2022205904 sameAs 2022205904 @default.
- W2022205904 citedByCount "93" @default.
- W2022205904 countsByYear W20222059042012 @default.
- W2022205904 countsByYear W20222059042013 @default.
- W2022205904 countsByYear W20222059042014 @default.
- W2022205904 countsByYear W20222059042015 @default.
- W2022205904 countsByYear W20222059042016 @default.
- W2022205904 countsByYear W20222059042017 @default.
- W2022205904 countsByYear W20222059042018 @default.
- W2022205904 countsByYear W20222059042020 @default.
- W2022205904 countsByYear W20222059042021 @default.
- W2022205904 countsByYear W20222059042022 @default.
- W2022205904 crossrefType "journal-article" @default.
- W2022205904 hasAuthorship W2022205904A5010532635 @default.
- W2022205904 hasAuthorship W2022205904A5047255137 @default.
- W2022205904 hasAuthorship W2022205904A5072162477 @default.
- W2022205904 hasBestOaLocation W20222059042 @default.
- W2022205904 hasConcept C111670793 @default.
- W2022205904 hasConcept C12554922 @default.
- W2022205904 hasConcept C134018914 @default.
- W2022205904 hasConcept C139369640 @default.
- W2022205904 hasConcept C147789679 @default.
- W2022205904 hasConcept C150903083 @default.
- W2022205904 hasConcept C160756335 @default.
- W2022205904 hasConcept C17525397 @default.
- W2022205904 hasConcept C178790620 @default.
- W2022205904 hasConcept C185592680 @default.
- W2022205904 hasConcept C202751555 @default.
- W2022205904 hasConcept C207001950 @default.
- W2022205904 hasConcept C25876315 @default.
- W2022205904 hasConcept C2777197210 @default.
- W2022205904 hasConcept C43617362 @default.
- W2022205904 hasConcept C52859227 @default.
- W2022205904 hasConcept C540031477 @default.
- W2022205904 hasConcept C55493867 @default.
- W2022205904 hasConcept C68801617 @default.
- W2022205904 hasConcept C77926170 @default.
- W2022205904 hasConcept C86803240 @default.
- W2022205904 hasConceptScore W2022205904C111670793 @default.
- W2022205904 hasConceptScore W2022205904C12554922 @default.
- W2022205904 hasConceptScore W2022205904C134018914 @default.
- W2022205904 hasConceptScore W2022205904C139369640 @default.