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- W2022207506 abstract "By the use of close arterial injection of leukotrienes into the circulation supplying the upper cervical canine trachea, it has been possible to assess the secretogogue effects of leukotriene C4, and D4 on mucus secretion. Both LTC4 and LTD4 increased mucus secretion over baseline levels by a statistically significant level (p = < 0.05). LTD4 was more potent than C4 with relative potencies of 2500, 320, 630, and 500 based on hillock formation (a measure of secretion) at 1, 2, 3, and 4 minutes after injection. The overall difference in potency in this animal model of mucus production was LTD4 > C4 by 1000-fold." @default.
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- W2022207506 date "1983-02-01" @default.
- W2022207506 modified "2023-09-23" @default.
- W2022207506 title "Secretogogue responses of leukotriene C4, D4: Comparison of potency in canine trachea" @default.
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- W2022207506 doi "https://doi.org/10.1016/0090-6980(83)90107-7" @default.
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