FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022207568> ?p ?o ?g. }

• W2022207568 endingPage "458" @default.
• W2022207568 startingPage "455" @default.
• W2022207568 abstract "The flowers of Chiranthodendron pentadactylon Larreat. (Sterculiaceae) has been traditionally used as folk medicine in Mexico for the treatment of gastrointestinal disorders such as diarrhea and dysentery.This study aimed to assess the antisecretory activity which supports the therapeutic use of Chiranthodendron pentadactylon and its flavonoids to treat diarrhea.The methanol extract of Chiranthodendron pentadactylon, subsequent fractions, and flavonoids were evaluated on cholera toxin-induced intestinal secretion in rat jejunal loops model.Three antisecretory flavonoids were isolated by bioassay-guided purification, namely, isoquercitrin 3, (+)-catechin 4 and (-)-epicatechin 5. Among them, epicatechin exhibited the most potent antisecretory activity with ID(50) of 8.3 microM/kg. Its potency was close that of to loperamide (ID(50) 6.1 microM/kg), drug used as control. Isoquercitrin (ID(50) 19.2 microM/kg) and catechin (ID(50) 51.7 microM/kg) showed moderate and weak activity, respectively.The results of the present study lend some support to the anecdotal report for the traditional use of the flowers of Chiranthodendron pentadactylon in the control of dysentery." @default.
• W2022207568 created "2016-06-24" @default.
• W2022207568 creator A5008148536 @default.
• W2022207568 creator A5010839458 @default.
• W2022207568 creator A5044485461 @default.
• W2022207568 creator A5064822938 @default.
• W2022207568 creator A5081823852 @default.
• W2022207568 date "2009-12-01" @default.
• W2022207568 modified "2023-10-01" @default.
• W2022207568 title "Antisecretory activity from the flowers of Chiranthodendron pentadactylon and its flavonoids on intestinal fluid accumulation induced by Vibrio cholerae toxin in rats" @default.
• W2022207568 cites W1971298088 @default.
• W2022207568 cites W1979235234 @default.
• W2022207568 cites W1979591484 @default.
• W2022207568 cites W2001373241 @default.
• W2022207568 cites W2002401098 @default.
• W2022207568 cites W2022709609 @default.
• W2022207568 cites W2024038647 @default.
• W2022207568 cites W2042464457 @default.
• W2022207568 cites W2072488506 @default.
• W2022207568 cites W2089848725 @default.
• W2022207568 cites W2093471180 @default.
• W2022207568 cites W2134323670 @default.
• W2022207568 cites W2940365551 @default.
• W2022207568 doi "https://doi.org/10.1016/j.jep.2009.09.016" @default.
• W2022207568 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19781621" @default.
• W2022207568 hasPublicationYear "2009" @default.
• W2022207568 type Work @default.
• W2022207568 sameAs 2022207568 @default.
• W2022207568 citedByCount "18" @default.
• W2022207568 countsByYear W20222075682012 @default.
• W2022207568 countsByYear W20222075682013 @default.
• W2022207568 countsByYear W20222075682014 @default.
• W2022207568 countsByYear W20222075682015 @default.
• W2022207568 countsByYear W20222075682017 @default.
• W2022207568 countsByYear W20222075682018 @default.
• W2022207568 countsByYear W20222075682019 @default.
• W2022207568 countsByYear W20222075682020 @default.
• W2022207568 countsByYear W20222075682022 @default.
• W2022207568 countsByYear W20222075682023 @default.
• W2022207568 crossrefType "journal-article" @default.
• W2022207568 hasAuthorship W2022207568A5008148536 @default.
• W2022207568 hasAuthorship W2022207568A5010839458 @default.
• W2022207568 hasAuthorship W2022207568A5044485461 @default.
• W2022207568 hasAuthorship W2022207568A5064822938 @default.
• W2022207568 hasAuthorship W2022207568A5081823852 @default.
• W2022207568 hasConcept C116073593 @default.
• W2022207568 hasConcept C126322002 @default.
• W2022207568 hasConcept C160492267 @default.
• W2022207568 hasConcept C202751555 @default.
• W2022207568 hasConcept C2777006276 @default.
• W2022207568 hasConcept C2777367657 @default.
• W2022207568 hasConcept C2777573665 @default.
• W2022207568 hasConcept C2778004101 @default.
• W2022207568 hasConcept C2778643871 @default.
• W2022207568 hasConcept C2779431889 @default.
• W2022207568 hasConcept C2779802037 @default.
• W2022207568 hasConcept C2780722889 @default.
• W2022207568 hasConcept C523546767 @default.
• W2022207568 hasConcept C54355233 @default.
• W2022207568 hasConcept C55493867 @default.
• W2022207568 hasConcept C556039675 @default.
• W2022207568 hasConcept C57992300 @default.
• W2022207568 hasConcept C70899900 @default.
• W2022207568 hasConcept C71924100 @default.
• W2022207568 hasConcept C86803240 @default.
• W2022207568 hasConcept C89423630 @default.
• W2022207568 hasConcept C98274493 @default.
• W2022207568 hasConceptScore W2022207568C116073593 @default.
• W2022207568 hasConceptScore W2022207568C126322002 @default.
• W2022207568 hasConceptScore W2022207568C160492267 @default.
• W2022207568 hasConceptScore W2022207568C202751555 @default.
• W2022207568 hasConceptScore W2022207568C2777006276 @default.
• W2022207568 hasConceptScore W2022207568C2777367657 @default.
• W2022207568 hasConceptScore W2022207568C2777573665 @default.
• W2022207568 hasConceptScore W2022207568C2778004101 @default.
• W2022207568 hasConceptScore W2022207568C2778643871 @default.
• W2022207568 hasConceptScore W2022207568C2779431889 @default.
• W2022207568 hasConceptScore W2022207568C2779802037 @default.
• W2022207568 hasConceptScore W2022207568C2780722889 @default.
• W2022207568 hasConceptScore W2022207568C523546767 @default.
• W2022207568 hasConceptScore W2022207568C54355233 @default.
• W2022207568 hasConceptScore W2022207568C55493867 @default.
• W2022207568 hasConceptScore W2022207568C556039675 @default.
• W2022207568 hasConceptScore W2022207568C57992300 @default.
• W2022207568 hasConceptScore W2022207568C70899900 @default.
• W2022207568 hasConceptScore W2022207568C71924100 @default.
• W2022207568 hasConceptScore W2022207568C86803240 @default.
• W2022207568 hasConceptScore W2022207568C89423630 @default.
• W2022207568 hasConceptScore W2022207568C98274493 @default.
• W2022207568 hasIssue "3" @default.
• W2022207568 hasLocation W20222075681 @default.
• W2022207568 hasLocation W20222075682 @default.
• W2022207568 hasOpenAccess W2022207568 @default.
• W2022207568 hasPrimaryLocation W20222075681 @default.
• W2022207568 hasRelatedWork W1758049144 @default.
• W2022207568 hasRelatedWork W2001360571 @default.
• W2022207568 hasRelatedWork W2030738655 @default.
• W2022207568 hasRelatedWork W2121963792 @default.

• next