FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022209332> ?p ?o ?g. }

• W2022209332 endingPage "24" @default.
• W2022209332 startingPage "24" @default.
• W2022209332 abstract "Background Only a few patients who experience AML relapse derive lasting benefit from re-induction therapy. The utility of reassessing the disease karyotype at relapse is unclear. The main goals of this study were to identify prognostic factors for AML relapse and to determine the prognostic utility of karyotypic change between diagnosis and relapse as a variable for predicting response to salvage therapy for relapsed AML. Methods This retrospective study included 58 patients with relapsed AML treated at the Yonsei University College of Medicine between 2005 and 2010. Karyotypes at both diagnosis and relapse were available for 45 patients (77%). A change in karyotype at relapse was observed in 17 of 45 cases (37%), and no change was noted in 28 of 45 cases (62%). Results Karyotypic changes between diagnosis and relapse were associated with the response rate (RR) to salvage therapy (P=0.016). Overall survival (OS) and event-free survival (EFS) in the group with karyotypic changes between diagnosis and relapse were significantly different from those with no karyotypic changes (P=0.004 and P=0.010, respectively). We applied multiple multivariate Cox regression analyses to identify independent prognostic factors for overall response (OR), OS, and EFS. A change in karyotype between diagnosis and relapse was significantly associated with OS (P=0.023; RR=2.655) and EFS (P=0.033; RR=2.831). Conclusion Karyotypic changes between the diagnosis and relapse of AML could be used to predict outcomes and tailor clinical and biological therapeutic strategies for relapsed AML patients." @default.
• W2022209332 created "2016-06-24" @default.
• W2022209332 creator A5003126278 @default.
• W2022209332 creator A5039335852 @default.
• W2022209332 creator A5043824226 @default.
• W2022209332 creator A5047765445 @default.
• W2022209332 creator A5063101533 @default.
• W2022209332 creator A5081285822 @default.
• W2022209332 creator A5088043851 @default.
• W2022209332 creator A5088824120 @default.
• W2022209332 date "2013-01-01" @default.
• W2022209332 modified "2023-09-29" @default.
• W2022209332 title "Karyotypic change between diagnosis and relapse as a predictor of salvage therapy outcome in AML patients" @default.
• W2022209332 cites W1481564836 @default.
• W2022209332 cites W1534965621 @default.
• W2022209332 cites W1860795225 @default.
• W2022209332 cites W2017645424 @default.
• W2022209332 cites W2025220839 @default.
• W2022209332 cites W2027227806 @default.
• W2022209332 cites W2057015804 @default.
• W2022209332 cites W2087597656 @default.
• W2022209332 cites W2089200614 @default.
• W2022209332 cites W2116858301 @default.
• W2022209332 cites W2150113701 @default.
• W2022209332 cites W2150917826 @default.
• W2022209332 cites W2159686776 @default.
• W2022209332 cites W2410089930 @default.
• W2022209332 doi "https://doi.org/10.5045/br.2013.48.1.24" @default.
• W2022209332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3624999" @default.
• W2022209332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23589791" @default.
• W2022209332 hasPublicationYear "2013" @default.
• W2022209332 type Work @default.
• W2022209332 sameAs 2022209332 @default.
• W2022209332 citedByCount "10" @default.
• W2022209332 countsByYear W20222093322014 @default.
• W2022209332 countsByYear W20222093322016 @default.
• W2022209332 countsByYear W20222093322017 @default.
• W2022209332 countsByYear W20222093322018 @default.
• W2022209332 countsByYear W20222093322019 @default.
• W2022209332 countsByYear W20222093322020 @default.
• W2022209332 countsByYear W20222093322021 @default.
• W2022209332 crossrefType "journal-article" @default.
• W2022209332 hasAuthorship W2022209332A5003126278 @default.
• W2022209332 hasAuthorship W2022209332A5039335852 @default.
• W2022209332 hasAuthorship W2022209332A5043824226 @default.
• W2022209332 hasAuthorship W2022209332A5047765445 @default.
• W2022209332 hasAuthorship W2022209332A5063101533 @default.
• W2022209332 hasAuthorship W2022209332A5081285822 @default.
• W2022209332 hasAuthorship W2022209332A5088043851 @default.
• W2022209332 hasAuthorship W2022209332A5088824120 @default.
• W2022209332 hasBestOaLocation W20222093321 @default.
• W2022209332 hasConcept C104317684 @default.
• W2022209332 hasConcept C126322002 @default.
• W2022209332 hasConcept C143998085 @default.
• W2022209332 hasConcept C164465091 @default.
• W2022209332 hasConcept C167135981 @default.
• W2022209332 hasConcept C2776694085 @default.
• W2022209332 hasConcept C2780775027 @default.
• W2022209332 hasConcept C30481170 @default.
• W2022209332 hasConcept C38180746 @default.
• W2022209332 hasConcept C50382708 @default.
• W2022209332 hasConcept C53226629 @default.
• W2022209332 hasConcept C55493867 @default.
• W2022209332 hasConcept C71924100 @default.
• W2022209332 hasConcept C86803240 @default.
• W2022209332 hasConceptScore W2022209332C104317684 @default.
• W2022209332 hasConceptScore W2022209332C126322002 @default.
• W2022209332 hasConceptScore W2022209332C143998085 @default.
• W2022209332 hasConceptScore W2022209332C164465091 @default.
• W2022209332 hasConceptScore W2022209332C167135981 @default.
• W2022209332 hasConceptScore W2022209332C2776694085 @default.
• W2022209332 hasConceptScore W2022209332C2780775027 @default.
• W2022209332 hasConceptScore W2022209332C30481170 @default.
• W2022209332 hasConceptScore W2022209332C38180746 @default.
• W2022209332 hasConceptScore W2022209332C50382708 @default.
• W2022209332 hasConceptScore W2022209332C53226629 @default.
• W2022209332 hasConceptScore W2022209332C55493867 @default.
• W2022209332 hasConceptScore W2022209332C71924100 @default.
• W2022209332 hasConceptScore W2022209332C86803240 @default.
• W2022209332 hasIssue "1" @default.
• W2022209332 hasLocation W20222093321 @default.
• W2022209332 hasLocation W20222093322 @default.
• W2022209332 hasLocation W20222093323 @default.
• W2022209332 hasLocation W20222093324 @default.
• W2022209332 hasOpenAccess W2022209332 @default.
• W2022209332 hasPrimaryLocation W20222093321 @default.
• W2022209332 hasRelatedWork W1995224362 @default.
• W2022209332 hasRelatedWork W2164958520 @default.
• W2022209332 hasRelatedWork W2361700749 @default.
• W2022209332 hasRelatedWork W2471181377 @default.
• W2022209332 hasRelatedWork W2892601847 @default.
• W2022209332 hasRelatedWork W2902684922 @default.
• W2022209332 hasRelatedWork W3093444689 @default.
• W2022209332 hasRelatedWork W3095136102 @default.
• W2022209332 hasRelatedWork W3194098699 @default.
• W2022209332 hasRelatedWork W4241233787 @default.
• W2022209332 hasVolume "48" @default.
• W2022209332 isParatext "false" @default.

• next