Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022210015> ?p ?o ?g. }
- W2022210015 endingPage "134" @default.
- W2022210015 startingPage "127" @default.
- W2022210015 abstract "Whether the combination of chronic kidney disease (CKD) and left ventricular hypertrophy (LVH) affects the cardiovascular (CV) risk in patients with uncomplicated hypertension is poorly investigated. The aim of this study was to assess the effects of LVH, CKD, and their combination on CV events in hypertension. This study analyzed 1,078 patients with essential hypertension. LVH was present in 104 (9.6%) patients, CKD was present in 556 (51.5%) patients, and the combination of LVH and CKD was found in 174 (16.1%) patients. During the follow-up (median = 84 months), 52 CV events were observed (0.64 events/100 patient-years): 6 (2.4%) in patients without target-organ damage (TOD), 6 (5.7%) in patients with LVH, 20 (3.6%) in patients with CKD, and 20 (11.4%) in patients with combined LVH+CKD. Adjusted hazard ratio (HR) for CV events was 1.62 (P = 0.34) for LVH, 0.951 (P = 0.94) for CKD, and 2.45 (P = 0.03) for LVH+CKD. After multivariable Cox proportional hazard analysis, the combination of LVH+CKD was significantly associated with risk of CV events, when the model was adjusted for sex and age (HR = 2.447; P = 0.03) and for the presence of 1 CV risk factor (HR = 3.226; P = 0.02). In contrast, the association of LVH+CKD was no longer significant when the model was adjusted for sex, age, and the presence of ≥2 CV risk factors. The results of this study highlight the relevance of the interactions between TODs and hemodynamic, anthropometric, and metabolic abnormalities in the CV risk stratification of patients with essential hypertension." @default.
- W2022210015 created "2016-06-24" @default.
- W2022210015 creator A5000170762 @default.
- W2022210015 creator A5010305162 @default.
- W2022210015 creator A5010543002 @default.
- W2022210015 creator A5013074872 @default.
- W2022210015 creator A5017161547 @default.
- W2022210015 creator A5020371820 @default.
- W2022210015 creator A5048882944 @default.
- W2022210015 creator A5072180984 @default.
- W2022210015 creator A5083637340 @default.
- W2022210015 date "2014-06-16" @default.
- W2022210015 modified "2023-10-01" @default.
- W2022210015 title "Prognostic Value of Combined Target-Organ Damage in Patients With Essential Hypertension" @default.
- W2022210015 cites W1965708830 @default.
- W2022210015 cites W1975240757 @default.
- W2022210015 cites W1977797884 @default.
- W2022210015 cites W1986931391 @default.
- W2022210015 cites W1992141724 @default.
- W2022210015 cites W1993639469 @default.
- W2022210015 cites W2001933911 @default.
- W2022210015 cites W2005019022 @default.
- W2022210015 cites W2022119110 @default.
- W2022210015 cites W2022584292 @default.
- W2022210015 cites W2031001127 @default.
- W2022210015 cites W2032576629 @default.
- W2022210015 cites W2034553362 @default.
- W2022210015 cites W2042293234 @default.
- W2022210015 cites W2048242978 @default.
- W2022210015 cites W2053816472 @default.
- W2022210015 cites W2072497790 @default.
- W2022210015 cites W2082236694 @default.
- W2022210015 cites W2082500143 @default.
- W2022210015 cites W2096073058 @default.
- W2022210015 cites W2101403562 @default.
- W2022210015 cites W2102177764 @default.
- W2022210015 cites W2106699876 @default.
- W2022210015 cites W2106761290 @default.
- W2022210015 cites W2119513877 @default.
- W2022210015 cites W2133217116 @default.
- W2022210015 cites W2154193616 @default.
- W2022210015 cites W2167128669 @default.
- W2022210015 cites W2275737843 @default.
- W2022210015 cites W2303651371 @default.
- W2022210015 cites W2317837592 @default.
- W2022210015 cites W4205288846 @default.
- W2022210015 cites W4238251256 @default.
- W2022210015 cites W4246016694 @default.
- W2022210015 doi "https://doi.org/10.1093/ajh/hpu098" @default.
- W2022210015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24936579" @default.
- W2022210015 hasPublicationYear "2014" @default.
- W2022210015 type Work @default.
- W2022210015 sameAs 2022210015 @default.
- W2022210015 citedByCount "17" @default.
- W2022210015 countsByYear W20222100152014 @default.
- W2022210015 countsByYear W20222100152016 @default.
- W2022210015 countsByYear W20222100152018 @default.
- W2022210015 countsByYear W20222100152020 @default.
- W2022210015 countsByYear W20222100152021 @default.
- W2022210015 countsByYear W20222100152022 @default.
- W2022210015 countsByYear W20222100152023 @default.
- W2022210015 crossrefType "journal-article" @default.
- W2022210015 hasAuthorship W2022210015A5000170762 @default.
- W2022210015 hasAuthorship W2022210015A5010305162 @default.
- W2022210015 hasAuthorship W2022210015A5010543002 @default.
- W2022210015 hasAuthorship W2022210015A5013074872 @default.
- W2022210015 hasAuthorship W2022210015A5017161547 @default.
- W2022210015 hasAuthorship W2022210015A5020371820 @default.
- W2022210015 hasAuthorship W2022210015A5048882944 @default.
- W2022210015 hasAuthorship W2022210015A5072180984 @default.
- W2022210015 hasAuthorship W2022210015A5083637340 @default.
- W2022210015 hasBestOaLocation W20222100151 @default.
- W2022210015 hasConcept C126322002 @default.
- W2022210015 hasConcept C164705383 @default.
- W2022210015 hasConcept C207103383 @default.
- W2022210015 hasConcept C2776002628 @default.
- W2022210015 hasConcept C2777097880 @default.
- W2022210015 hasConcept C2778653478 @default.
- W2022210015 hasConcept C44249647 @default.
- W2022210015 hasConcept C50382708 @default.
- W2022210015 hasConcept C50440223 @default.
- W2022210015 hasConcept C71924100 @default.
- W2022210015 hasConcept C84393581 @default.
- W2022210015 hasConceptScore W2022210015C126322002 @default.
- W2022210015 hasConceptScore W2022210015C164705383 @default.
- W2022210015 hasConceptScore W2022210015C207103383 @default.
- W2022210015 hasConceptScore W2022210015C2776002628 @default.
- W2022210015 hasConceptScore W2022210015C2777097880 @default.
- W2022210015 hasConceptScore W2022210015C2778653478 @default.
- W2022210015 hasConceptScore W2022210015C44249647 @default.
- W2022210015 hasConceptScore W2022210015C50382708 @default.
- W2022210015 hasConceptScore W2022210015C50440223 @default.
- W2022210015 hasConceptScore W2022210015C71924100 @default.
- W2022210015 hasConceptScore W2022210015C84393581 @default.
- W2022210015 hasIssue "1" @default.
- W2022210015 hasLocation W20222100151 @default.
- W2022210015 hasLocation W20222100152 @default.
- W2022210015 hasOpenAccess W2022210015 @default.