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- W2022211275 abstract "To evaluate maternal total vascular resistance (TVR) in asymptomatic primigravidae with persisting bilateral notching of uterine arteries Doppler waveforms after 24 weeks' gestation. 104 selected patients with bilateral notching underwent maternal echocardiographic examination at 24 weeks' gestation. Fetal and maternal outcomes were verified at the end of pregnancy and TVR was compared between patients with and patients without complications. A ROC curve was built for TVR to find the best cut-off value for maternal and/or fetal complications. 59 (56.7%) women subsequentely showed a normal outcome of pregnancy; 45 (43.3%) patients developed an abnormal outcome of pregnancy (gestational hypertension, growth restriction, pre-eclampsia). TVR in the uncomplicated group was 1081 ± 286 dyne s cm−5; TVR in the complicated group was 1558 ± 275 dyne s cm−5 (P < 0.00001). The cut-off value of TVR was 1400 dyne s cm−5. X2 test for TVR > 1400 dyne s cm−5 showed sensitivity, specificity, positive and negative predictive values of 91%, 97%, 95% and 93%, respectively. Calculations of TVR might help in the identification of cardiovascular maladaptation in patients with persisting bilateral notch of the uterine artery. Elevated TVR are linked to the development of subsequent clinical complications." @default.
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- W2022211275 date "2007-09-21" @default.
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- W2022211275 title "OP01.04: Total vascular resistance is already elevated at 24 weeks' gestation in patients with subsequent complications in persisting bilateral notching of uterine artery Doppler waveforms" @default.
- W2022211275 doi "https://doi.org/10.1002/uog.4393" @default.
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