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- W2022212108 abstract "We investigated the mRNA levels of interleukin-6-related genes in a rat dorsal root ganglion after application of a tourniquet to a hind limb in order to identify the molecules that are induced immediately after peripheral nerve injury at the early stage. Induction of interleukin-6 and upregulation of glycoprotein 130 mRNA expressions were observed in the ipsilateral dorsal root ganglion at 4 h after tourniquet application. Interleukin-6 protein was detected in small-sized and medium-sized dorsal root ganglion cells by immunohistochemical analysis. The induction of interleukin-6 expression is likely to play a role in the protection of injured neurons perhaps related to growth of their axons. Glycoprotein 130 might also account for the inhibitory effects following nerve injury." @default.
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- W2022212108 date "2005-11-28" @default.
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- W2022212108 title "A hind limb tourniquet induces interleukin-6 expression in a rat dorsal root ganglion" @default.
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- W2022212108 doi "https://doi.org/10.1097/01.wnr.0000186600.73867.8a" @default.
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