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- W2022226777 abstract "The sensitivity of an inhibition enzyme-linked immunosorbent assay (ELISA), which detected serum antibodies against a Borrelia-specific epitope, located at amino acid positions 208–224 of the flagellin of Borrelia burgdorferi, was compared with an IgG flagellum ELISA. The inhibition ELISA proved to be slightly more sensitive in detecting antibodies in sera of erythema migrans patients than the IgG flagellum ELISA (61 vs. 52% positive). Seven of 61 Lyme borreliosis sera gave discrepant reactions between both tests. Western blot analysis confirmed the result of the inhibition ELISA in five of these samples. These results demonstrate the importance of this flagellar epitope for serodiagnosis and suggest that the inhibition ELISA is useful as a confirmation assay. This assay can also be used to detect B. burgdorferi antibodies from a variety of animal species." @default.
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- W2022226777 date "1994-07-01" @default.
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- W2022226777 title "Serum antibodies to the flagellum of Borrelia burgdorferi measured with an inhibition enzyme-linked immunosorbent assay are diagnostic for Lyme borreliosis" @default.
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- W2022226777 doi "https://doi.org/10.1016/0888-0786(94)90047-7" @default.
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