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- W2022231030 abstract "Using a high performance liquid chromatography method, degradation products of heparan sulfate (HS) and dermatan sulfate (DS) were investigated after incubation of control and α-l-iduronidase-deficient fibroblasts with HS or DS. Characteristic elution profiles of the degradation products were obtained from the respective α-l-iduronidase-deficient fibroblasts. Moreover, α-l-iduronidase in control fibroblasts was resolved into two distinct components, forms A and B, on DEAE-cellulose column chromatography. Form A α-l-iduronidase could degrade HS, but not DS. Conversely, form B α-l-iduronidase could not degrade HS, but could degrade DS." @default.
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- W2022231030 date "1984-02-01" @default.
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- W2022231030 title "Heparan sulfate and dermatan sulfate from the liver of a patient with Hurler syndrome: high performance liquid chromatography of their degradation products after incubation with α-l-iduronidase-deficient fibroblasts" @default.
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- W2022231030 doi "https://doi.org/10.1016/0009-8981(84)90178-5" @default.
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