Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022237231> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2022237231 endingPage "1657" @default.
- W2022237231 startingPage "1653" @default.
- W2022237231 abstract "A new hepatitis-associated RNA virus of the Flaviviridae family has been identified and named GB virus C/ hepatitis G virus (HGV). We carried out a case-control study to evaluate the association of HGV infection with hepatocellular carcinoma (HCC). We recruited 170 patients hospitalized for HCC (143 male and 27 female, mean age 64 years) and 306 patients hospitalized for nonliver diseases (controls) in Brescia, Italy. HGV RNA was detected by reverse transcription-polymerase chain reaction (RT-PCR) and antibodies against HGV E2 protein (anti-E2) by an immunoassay test. HGV RNA was found in 8 cases (4.7%) and 4 controls (1.3%). The relative risk (RR) for HGV RNA positivity adjusted for demographic variables and hepatitis B surface antigen (HBsAg), hepatitis C virus (HCV) RNA, and alcohol was 7.3 (95% confidence interval, 1.7-30.6; P = .009). No HGV RNA-positive subject was also positive for anti-E2. Anti-E2 prevalence did not differ significantly between cases (20%) and controls (15.3%), and no RR increase was found by this marker. Among subjects with HGV exposure (HGV RNA plus anti-E2 positive), a greater proportion of cases (40%) than controls (14%) had transfusion history. The possible role of HGV in HCC etiology seems modest because the population-attributable risk is lower (4%) than those for HBsAg (22%), HCV RNA (36%), and heavy alcohol intake (52%). This study supports the hypothesis of an association between HGV infection and HCC, although at present there are insufficient data on the causality of the association." @default.
- W2022237231 created "2016-06-24" @default.
- W2022237231 creator A5007446668 @default.
- W2022237231 creator A5008026098 @default.
- W2022237231 creator A5017145190 @default.
- W2022237231 creator A5039322667 @default.
- W2022237231 creator A5068366647 @default.
- W2022237231 creator A5076058600 @default.
- W2022237231 creator A5084094376 @default.
- W2022237231 creator A5087256602 @default.
- W2022237231 creator A5089251379 @default.
- W2022237231 creator A5090665664 @default.
- W2022237231 date "1997-12-01" @default.
- W2022237231 modified "2023-09-24" @default.
- W2022237231 title "A case-control study on GB virus C/hepatitis G virus infection and hepatocellular carcinoma. Brescia HCC Study" @default.
- W2022237231 doi "https://doi.org/10.1053/jhep.1997.v26.pm0009398012" @default.
- W2022237231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9398012" @default.
- W2022237231 hasPublicationYear "1997" @default.
- W2022237231 type Work @default.
- W2022237231 sameAs 2022237231 @default.
- W2022237231 citedByCount "15" @default.
- W2022237231 countsByYear W20222372312013 @default.
- W2022237231 countsByYear W20222372312022 @default.
- W2022237231 crossrefType "journal-article" @default.
- W2022237231 hasAuthorship W2022237231A5007446668 @default.
- W2022237231 hasAuthorship W2022237231A5008026098 @default.
- W2022237231 hasAuthorship W2022237231A5017145190 @default.
- W2022237231 hasAuthorship W2022237231A5039322667 @default.
- W2022237231 hasAuthorship W2022237231A5068366647 @default.
- W2022237231 hasAuthorship W2022237231A5076058600 @default.
- W2022237231 hasAuthorship W2022237231A5084094376 @default.
- W2022237231 hasAuthorship W2022237231A5087256602 @default.
- W2022237231 hasAuthorship W2022237231A5089251379 @default.
- W2022237231 hasAuthorship W2022237231A5090665664 @default.
- W2022237231 hasConcept C126322002 @default.
- W2022237231 hasConcept C159047783 @default.
- W2022237231 hasConcept C203014093 @default.
- W2022237231 hasConcept C2522874641 @default.
- W2022237231 hasConcept C2776408679 @default.
- W2022237231 hasConcept C2777072776 @default.
- W2022237231 hasConcept C2777410769 @default.
- W2022237231 hasConcept C2777510210 @default.
- W2022237231 hasConcept C2778019345 @default.
- W2022237231 hasConcept C2780593183 @default.
- W2022237231 hasConcept C2780847992 @default.
- W2022237231 hasConcept C71924100 @default.
- W2022237231 hasConceptScore W2022237231C126322002 @default.
- W2022237231 hasConceptScore W2022237231C159047783 @default.
- W2022237231 hasConceptScore W2022237231C203014093 @default.
- W2022237231 hasConceptScore W2022237231C2522874641 @default.
- W2022237231 hasConceptScore W2022237231C2776408679 @default.
- W2022237231 hasConceptScore W2022237231C2777072776 @default.
- W2022237231 hasConceptScore W2022237231C2777410769 @default.
- W2022237231 hasConceptScore W2022237231C2777510210 @default.
- W2022237231 hasConceptScore W2022237231C2778019345 @default.
- W2022237231 hasConceptScore W2022237231C2780593183 @default.
- W2022237231 hasConceptScore W2022237231C2780847992 @default.
- W2022237231 hasConceptScore W2022237231C71924100 @default.
- W2022237231 hasIssue "6" @default.
- W2022237231 hasLocation W20222372311 @default.
- W2022237231 hasLocation W20222372312 @default.
- W2022237231 hasOpenAccess W2022237231 @default.
- W2022237231 hasPrimaryLocation W20222372311 @default.
- W2022237231 hasRelatedWork W1435627280 @default.
- W2022237231 hasRelatedWork W2009600510 @default.
- W2022237231 hasRelatedWork W2015824057 @default.
- W2022237231 hasRelatedWork W2022237231 @default.
- W2022237231 hasRelatedWork W2029008013 @default.
- W2022237231 hasRelatedWork W2083266836 @default.
- W2022237231 hasRelatedWork W2125120082 @default.
- W2022237231 hasRelatedWork W2416453027 @default.
- W2022237231 hasRelatedWork W2470164809 @default.
- W2022237231 hasRelatedWork W39399998 @default.
- W2022237231 hasVolume "26" @default.
- W2022237231 isParatext "false" @default.
- W2022237231 isRetracted "false" @default.
- W2022237231 magId "2022237231" @default.
- W2022237231 workType "article" @default.