Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022237929> ?p ?o ?g. }
- W2022237929 endingPage "775" @default.
- W2022237929 startingPage "771" @default.
- W2022237929 abstract "This paper reports an experimental study of the interference of GTP hydrolysis in the mechanism of microtubule assembly, following the model and theory previously published [Hill, T. L. & Carlier, M.-F. (1983) Proc. Natl. Acad. Sci. USA 80, 7234-7238]. Results from dilution experiments show that microtubules depolymerize faster below the critical concentration than expected with a reversible polymerization model. The experimental plot of flux versus tubulin concentration exhibits a slope discontinuity at the critical concentration, in agreement with the theory. Theoretical points calculated by the Monte Carlo method can be fitted qualitatively to the data. A consequence of this peculiar dynamic behavior of microtubules is that the ratio of tubulin dissociation and association rate constants measured, respectively, below and above the critical concentration does not yield the true value of the critical concentration. It is emphasized that the presence of GTP at microtubule ends is necessary to maintain the stability of the polymer." @default.
- W2022237929 created "2016-06-24" @default.
- W2022237929 creator A5007663113 @default.
- W2022237929 creator A5032162314 @default.
- W2022237929 creator A5091304112 @default.
- W2022237929 date "1984-02-01" @default.
- W2022237929 modified "2023-10-14" @default.
- W2022237929 title "Interference of GTP hydrolysis in the mechanism of microtubule assembly: an experimental study." @default.
- W2022237929 cites W1497333828 @default.
- W2022237929 cites W1501340983 @default.
- W2022237929 cites W1536856196 @default.
- W2022237929 cites W1569063010 @default.
- W2022237929 cites W1775749144 @default.
- W2022237929 cites W1965137443 @default.
- W2022237929 cites W1965541346 @default.
- W2022237929 cites W1968635852 @default.
- W2022237929 cites W1975040221 @default.
- W2022237929 cites W1983776866 @default.
- W2022237929 cites W1995355570 @default.
- W2022237929 cites W1997572632 @default.
- W2022237929 cites W2003468593 @default.
- W2022237929 cites W2005314799 @default.
- W2022237929 cites W2007785335 @default.
- W2022237929 cites W2010567389 @default.
- W2022237929 cites W2011521398 @default.
- W2022237929 cites W2014636427 @default.
- W2022237929 cites W2022993744 @default.
- W2022237929 cites W2034304466 @default.
- W2022237929 cites W2034677151 @default.
- W2022237929 cites W2035319786 @default.
- W2022237929 cites W2037811434 @default.
- W2022237929 cites W2039303292 @default.
- W2022237929 cites W2043029866 @default.
- W2022237929 cites W2057337811 @default.
- W2022237929 cites W2061637739 @default.
- W2022237929 cites W2064993724 @default.
- W2022237929 cites W2075893848 @default.
- W2022237929 cites W2088677348 @default.
- W2022237929 cites W2089886351 @default.
- W2022237929 cites W2094646664 @default.
- W2022237929 cites W2115876454 @default.
- W2022237929 cites W2317659315 @default.
- W2022237929 cites W8869034 @default.
- W2022237929 doi "https://doi.org/10.1073/pnas.81.3.771" @default.
- W2022237929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/344918" @default.
- W2022237929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6583675" @default.
- W2022237929 hasPublicationYear "1984" @default.
- W2022237929 type Work @default.
- W2022237929 sameAs 2022237929 @default.
- W2022237929 citedByCount "149" @default.
- W2022237929 countsByYear W20222379292012 @default.
- W2022237929 countsByYear W20222379292013 @default.
- W2022237929 countsByYear W20222379292014 @default.
- W2022237929 countsByYear W20222379292015 @default.
- W2022237929 countsByYear W20222379292016 @default.
- W2022237929 countsByYear W20222379292017 @default.
- W2022237929 countsByYear W20222379292018 @default.
- W2022237929 countsByYear W20222379292019 @default.
- W2022237929 countsByYear W20222379292020 @default.
- W2022237929 countsByYear W20222379292021 @default.
- W2022237929 countsByYear W20222379292022 @default.
- W2022237929 crossrefType "journal-article" @default.
- W2022237929 hasAuthorship W2022237929A5007663113 @default.
- W2022237929 hasAuthorship W2022237929A5032162314 @default.
- W2022237929 hasAuthorship W2022237929A5091304112 @default.
- W2022237929 hasBestOaLocation W20222379292 @default.
- W2022237929 hasConcept C102931765 @default.
- W2022237929 hasConcept C105795698 @default.
- W2022237929 hasConcept C118716 @default.
- W2022237929 hasConcept C121332964 @default.
- W2022237929 hasConcept C12554922 @default.
- W2022237929 hasConcept C147789679 @default.
- W2022237929 hasConcept C181199279 @default.
- W2022237929 hasConcept C185592680 @default.
- W2022237929 hasConcept C19499675 @default.
- W2022237929 hasConcept C20418707 @default.
- W2022237929 hasConcept C33923547 @default.
- W2022237929 hasConcept C55493867 @default.
- W2022237929 hasConcept C84425145 @default.
- W2022237929 hasConcept C86803240 @default.
- W2022237929 hasConcept C95444343 @default.
- W2022237929 hasConcept C96618451 @default.
- W2022237929 hasConcept C97355855 @default.
- W2022237929 hasConceptScore W2022237929C102931765 @default.
- W2022237929 hasConceptScore W2022237929C105795698 @default.
- W2022237929 hasConceptScore W2022237929C118716 @default.
- W2022237929 hasConceptScore W2022237929C121332964 @default.
- W2022237929 hasConceptScore W2022237929C12554922 @default.
- W2022237929 hasConceptScore W2022237929C147789679 @default.
- W2022237929 hasConceptScore W2022237929C181199279 @default.
- W2022237929 hasConceptScore W2022237929C185592680 @default.
- W2022237929 hasConceptScore W2022237929C19499675 @default.
- W2022237929 hasConceptScore W2022237929C20418707 @default.
- W2022237929 hasConceptScore W2022237929C33923547 @default.
- W2022237929 hasConceptScore W2022237929C55493867 @default.
- W2022237929 hasConceptScore W2022237929C84425145 @default.
- W2022237929 hasConceptScore W2022237929C86803240 @default.
- W2022237929 hasConceptScore W2022237929C95444343 @default.