FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022238225> ?p ?o ?g. }

• W2022238225 endingPage "605" @default.
• W2022238225 startingPage "605" @default.
• W2022238225 abstract "Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence Norio Watanabe,1,2 Keiko Yamamura,3 Yusuke Suzuki,4 Hiroyuki Umegaki,4 Katsuro Shigeno,5 Ryo Matsushita,1 Yoshimichi Sai,1 Ken-ichi Miyamoto,1 Kiyofumi Yamada61Department of Clinical Pharmacy, Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa, Ishikawa, Japan; 2Department of Pharmacy, Hashima Municipal Hospital, Hashima, Gifu, Japan; 3Department of Clinical Pharmacy, School of Pharmacy, Aichi Gakuin University, Nagoya, Aichi, Japan; 4Department of Community Healthcare and Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan; 5Department of Pharmacy Practice and Sciences, School of Pharmacy, Aichi Gakuin University, Nagoya, Aichi, Japan; 6Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya, Aichi, JapanAim: Donepezil is widely used to delay the progression of cognitive dysfunction in patients with Alzheimer&#39;s disease (AD), but the efficacy of pharmacotherapy is often reduced by poor adherence to medication. In order to improve adherence by providing information about AD and the significance of pharmacotherapy, the Donepezil Outpatient Consultation Service (DOCS) was set up. The influence of this service on medication persistence was assessed in the present study.Methods: Among outpatients starting donepezil therapy, we enrolled 59 patients between April 2008 and September 2010 before establishment of the DOCS (non-DOCS group) and 52 patients between October 2010 and March 2012 who attended the DOCS (DOCS group). Each patient&#39;s and their caregiver&#39;s understanding about the clinical features of AD and pharmacotherapy with donepezil were also assessed. Their understanding was compared before and after the DOCS, and the 1-year medication persistence rate and the reasons for discontinuation were also investigated.Results: The 1-year medication persistence rate was significantly higher in the DOCS group than in the non-DOCS group (73.1% vs 49.2%, P = 0.008). We examined the association of medication persistence with age, sex, clinical dementia rating, living alone, and attending the DOCS. As a result, medication persistence was significantly higher in patients attending the DOCS. The main reasons for discontinuation of donepezil were transfer elsewhere (11) and gastrointestinal side effects (5) in the non-DOCS group, and transfer (9) and gastrointestinal side effects (3) in the DOCS group. The overall score for understanding was 2.5 ± 1.7 before attending the DOCS and it increased significantly to 5.7 ± 0.7 afterward (P < 0.001).Conclusion: The DOCS consultation provided by hospital pharmacists for AD patients and their caregivers improved understanding about the clinical features of dementia and provided pharmacological knowledge about antidementia drugs, leading to better adherence to pharmacotherapy that could maximize its effect.Keywords: Alzheimer&#39;s disease, cholinesterase inhibitors, consultation, donepezil, patient knowledge, pharmacists" @default.
• W2022238225 created "2016-06-24" @default.
• W2022238225 creator A5001620097 @default.
• W2022238225 creator A5041725712 @default.
• W2022238225 creator A5054512864 @default.
• W2022238225 creator A5063611864 @default.
• W2022238225 creator A5074635182 @default.
• W2022238225 creator A5078105410 @default.
• W2022238225 creator A5079133376 @default.
• W2022238225 creator A5080991905 @default.
• W2022238225 creator A5085519303 @default.
• W2022238225 date "2012-08-01" @default.
• W2022238225 modified "2023-10-18" @default.
• W2022238225 title "Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence" @default.
• W2022238225 cites W1575078744 @default.
• W2022238225 cites W1969970226 @default.
• W2022238225 cites W2026659454 @default.
• W2022238225 cites W2044212781 @default.
• W2022238225 cites W2047095305 @default.
• W2022238225 cites W2061533312 @default.
• W2022238225 cites W2081401515 @default.
• W2022238225 cites W2089156337 @default.
• W2022238225 cites W2101265858 @default.
• W2022238225 cites W2151918054 @default.
• W2022238225 cites W2414565701 @default.
• W2022238225 cites W960146918 @default.
• W2022238225 doi "https://doi.org/10.2147/ppa.s34984" @default.
• W2022238225 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3437908" @default.
• W2022238225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22969291" @default.
• W2022238225 hasPublicationYear "2012" @default.
• W2022238225 type Work @default.
• W2022238225 sameAs 2022238225 @default.
• W2022238225 citedByCount "12" @default.
• W2022238225 countsByYear W20222382252014 @default.
• W2022238225 countsByYear W20222382252015 @default.
• W2022238225 countsByYear W20222382252016 @default.
• W2022238225 countsByYear W20222382252017 @default.
• W2022238225 countsByYear W20222382252018 @default.
• W2022238225 countsByYear W20222382252021 @default.
• W2022238225 countsByYear W20222382252022 @default.
• W2022238225 countsByYear W20222382252023 @default.
• W2022238225 crossrefType "journal-article" @default.
• W2022238225 hasAuthorship W2022238225A5001620097 @default.
• W2022238225 hasAuthorship W2022238225A5041725712 @default.
• W2022238225 hasAuthorship W2022238225A5054512864 @default.
• W2022238225 hasAuthorship W2022238225A5063611864 @default.
• W2022238225 hasAuthorship W2022238225A5074635182 @default.
• W2022238225 hasAuthorship W2022238225A5078105410 @default.
• W2022238225 hasAuthorship W2022238225A5079133376 @default.
• W2022238225 hasAuthorship W2022238225A5080991905 @default.
• W2022238225 hasAuthorship W2022238225A5085519303 @default.
• W2022238225 hasBestOaLocation W20222382251 @default.
• W2022238225 hasConcept C10446079 @default.
• W2022238225 hasConcept C104863432 @default.
• W2022238225 hasConcept C118552586 @default.
• W2022238225 hasConcept C126322002 @default.
• W2022238225 hasConcept C2779134260 @default.
• W2022238225 hasConcept C2779457091 @default.
• W2022238225 hasConcept C2779483572 @default.
• W2022238225 hasConcept C2780904820 @default.
• W2022238225 hasConcept C500440147 @default.
• W2022238225 hasConcept C512399662 @default.
• W2022238225 hasConcept C54183767 @default.
• W2022238225 hasConcept C71924100 @default.
• W2022238225 hasConceptScore W2022238225C10446079 @default.
• W2022238225 hasConceptScore W2022238225C104863432 @default.
• W2022238225 hasConceptScore W2022238225C118552586 @default.
• W2022238225 hasConceptScore W2022238225C126322002 @default.
• W2022238225 hasConceptScore W2022238225C2779134260 @default.
• W2022238225 hasConceptScore W2022238225C2779457091 @default.
• W2022238225 hasConceptScore W2022238225C2779483572 @default.
• W2022238225 hasConceptScore W2022238225C2780904820 @default.
• W2022238225 hasConceptScore W2022238225C500440147 @default.
• W2022238225 hasConceptScore W2022238225C512399662 @default.
• W2022238225 hasConceptScore W2022238225C54183767 @default.
• W2022238225 hasConceptScore W2022238225C71924100 @default.
• W2022238225 hasLocation W20222382251 @default.
• W2022238225 hasLocation W20222382252 @default.
• W2022238225 hasLocation W20222382253 @default.
• W2022238225 hasOpenAccess W2022238225 @default.
• W2022238225 hasPrimaryLocation W20222382251 @default.
• W2022238225 hasRelatedWork W1995800213 @default.
• W2022238225 hasRelatedWork W2052892900 @default.
• W2022238225 hasRelatedWork W2260182467 @default.
• W2022238225 hasRelatedWork W2391422502 @default.
• W2022238225 hasRelatedWork W2416235114 @default.
• W2022238225 hasRelatedWork W2725236363 @default.
• W2022238225 hasRelatedWork W2749406675 @default.
• W2022238225 hasRelatedWork W2954475304 @default.
• W2022238225 hasRelatedWork W3081988447 @default.
• W2022238225 hasRelatedWork W2949077388 @default.
• W2022238225 isParatext "false" @default.
• W2022238225 isRetracted "false" @default.
• W2022238225 magId "2022238225" @default.
• W2022238225 workType "article" @default.