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• W2022239093 endingPage "351" @default.
• W2022239093 startingPage "351" @default.
• W2022239093 abstract "In the present study, selenium (Se) nanoclusters were grown through heterogeneous nucleation on titanium (Ti) surfaces, a common orthopedic implant material. Normal healthy osteoblasts (bone-forming cells) and cancerous osteoblasts (osteosarcoma) were cultured on the Se-doped surfaces having three different coating densities. For the first time, it is shown that substrates with Se nanoclusters promote normal osteoblast proliferation and inhibit cancerous osteoblast growth in both separate (mono-culture) and coculture experiment. This study suggests that Se surface nanoclusters can be properly engineered to inhibit bone cancer growth while simultaneously promoting the growth of normal bone tissue." @default.
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• W2022239093 date "2010-05-01" @default.
• W2022239093 modified "2023-09-30" @default.
• W2022239093 title "Differential effects of nanoselenium doping on healthy and cancerous osteoblasts in coculture on titanium" @default.
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• W2022239093 doi "https://doi.org/10.2147/ijn.s7289" @default.
• W2022239093 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2875729" @default.
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