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• W2022242849 abstract "Boron nitride nanotubes (BNNTs) are tubular nanoparticles with a structure analogous to that of carbon nanotubes, but with B and N atoms that completely replace the C atoms. Many favorable results indicate BNNTs as safe nanomaterials; however, important concerns have recently been raised about ultra-pure, long (~10 µm) BNNTs tested on several cell types.Here, we propose additional experiments with the same BNNTs, but shortened (~1.5 µm) with a homogenization/sonication treatment that allows for their dispersion in gum Arabic aqueous solutions. Obtained BNNTs are tested on human endothelial and neuron-like cells with several independent biocompatibility assays. Moreover, for the first time, their strong sum-frequency generation signal is exploited to assess the cellular uptake.Our data demonstrate no toxic effects up to concentrations of 20 µg/ml, once more confirming biosafety of BNNTs, and again highlighting that nanoparticle aspect ratio plays a key role in the biocompatibility evaluation." @default.
• W2022242849 created "2016-06-24" @default.
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• W2022242849 date "2014-05-01" @default.
• W2022242849 modified "2023-10-12" @default.
• W2022242849 title "Cytocompatibility evaluation of gum Arabic-coated ultra-pure boron nitride nanotubes on human cells" @default.
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• W2022242849 doi "https://doi.org/10.2217/nnm.14.25" @default.
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