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- W2022246654 abstract "Various studies on the natural history of coronary artery disease have demonstrated that the prognosis of the disease is directly related to its severity and to the degree of associated left ventricular dysfunction as defined primarily with coronary angiography and ventriculography.l-g Two and three vessel coronary artery disease and stenosis of the left main coronary artery appear to have a poor prognosis, and the 5 to 10 year outlook is even worse when they are associated with factors such as left ventricular dysfunction, abnormal electrocardiogram, hypertension, cardiomegaly and congestive heart failure l-l5 The ‘natural history studies have also shown that patients with single vessel coronary artery disease have a better 5 to 10 year survival rate than patients with double or triple vessel disease.1-2*5-8 However, their prognosis appears to differ according to whether the vessel involved is the left anterior descending, left circumflex or right coronary artery.1*2>5v7-g In view of the surgical implications, we will examine the hypothesis that significant disease isolated to the left anterior descending coronary artery is more lethal than any other single vessel coronary disease. This will be examined with three approaches-myocardial infarction studies, angiographic data and data on surgical versus medical treatment." @default.
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- W2022246654 date "1977-10-01" @default.
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- W2022246654 title "Isolated left anterior descending coronary artery disease: Choice of therapy" @default.
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- W2022246654 doi "https://doi.org/10.1016/0002-9149(77)90086-8" @default.
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