FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022246976> ?p ?o ?g. }

• W2022246976 endingPage "103" @default.
• W2022246976 startingPage "93" @default.
• W2022246976 abstract "The extension and directionality of neurite outgrowth are key to achieving successful target connections during both CNS development and during the re-establishment of connections lost after neural trauma. The degree of axonal elongation depends, in large part, on the spatial arrangement of astrocytic processes rich in growth-promoting proteins. Because astrocytes in culture align their processes on exposure to an electrical field of physiological strength, we sought to determine the extent to which aligned astrocytes affect neurite outgrowth. To this end, dorsal root ganglia cells were seeded onto cultured rat astrocytes that were pre-aligned by exposure to an electric field of physiological strength (500 mV mm −1 ). Using confocal microscopy and digital image analysis, we found that neurite outgrowth at 24 hours and at 48 hours is enhanced significantly and directed consistently along the aligned astrocyte processes. Moreover, this directed neurite outgrowth is maintained when grown on fixed, aligned astrocytes. Collectively, these results indicate that endogenous electric fields present within the developing CNS might act to align astrocyte processes, which can promote and direct neurite growth. Furthermore, these results demonstrate a simple method to produce an aligned cellular substrate, which might be used to direct regenerating neurites." @default.
• W2022246976 created "2016-06-24" @default.
• W2022246976 creator A5025939467 @default.
• W2022246976 creator A5032202964 @default.
• W2022246976 creator A5052653055 @default.
• W2022246976 date "2006-01-23" @default.
• W2022246976 modified "2023-10-14" @default.
• W2022246976 title "Electric field-induced astrocyte alignment directs neurite outgrowth" @default.
• W2022246976 cites W1500951255 @default.
• W2022246976 cites W1566509581 @default.
• W2022246976 cites W1570841376 @default.
• W2022246976 cites W1916984064 @default.
• W2022246976 cites W1945237426 @default.
• W2022246976 cites W1964936262 @default.
• W2022246976 cites W1970388007 @default.
• W2022246976 cites W1973524445 @default.
• W2022246976 cites W1997087466 @default.
• W2022246976 cites W2001310533 @default.
• W2022246976 cites W2003801257 @default.
• W2022246976 cites W2004185615 @default.
• W2022246976 cites W2011061147 @default.
• W2022246976 cites W2025625968 @default.
• W2022246976 cites W2029536919 @default.
• W2022246976 cites W2031556847 @default.
• W2022246976 cites W2034363051 @default.
• W2022246976 cites W2039422279 @default.
• W2022246976 cites W2040840739 @default.
• W2022246976 cites W2042162852 @default.
• W2022246976 cites W2044177309 @default.
• W2022246976 cites W2056053144 @default.
• W2022246976 cites W2059994807 @default.
• W2022246976 cites W2065179254 @default.
• W2022246976 cites W2069885684 @default.
• W2022246976 cites W2073098490 @default.
• W2022246976 cites W2078826387 @default.
• W2022246976 cites W2092500174 @default.
• W2022246976 cites W2107676779 @default.
• W2022246976 cites W2109811832 @default.
• W2022246976 cites W2109888276 @default.
• W2022246976 cites W2123450039 @default.
• W2022246976 cites W2147208594 @default.
• W2022246976 cites W2148304597 @default.
• W2022246976 cites W2149130993 @default.
• W2022246976 cites W2154107855 @default.
• W2022246976 cites W2158015730 @default.
• W2022246976 cites W2167297493 @default.
• W2022246976 cites W2221064544 @default.
• W2022246976 doi "https://doi.org/10.1017/s1740925x0600010x" @default.
• W2022246976 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2367316" @default.
• W2022246976 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18458757" @default.
• W2022246976 hasPublicationYear "2006" @default.
• W2022246976 type Work @default.
• W2022246976 sameAs 2022246976 @default.
• W2022246976 citedByCount "125" @default.
• W2022246976 countsByYear W20222469762012 @default.
• W2022246976 countsByYear W20222469762013 @default.
• W2022246976 countsByYear W20222469762014 @default.
• W2022246976 countsByYear W20222469762015 @default.
• W2022246976 countsByYear W20222469762016 @default.
• W2022246976 countsByYear W20222469762017 @default.
• W2022246976 countsByYear W20222469762018 @default.
• W2022246976 countsByYear W20222469762019 @default.
• W2022246976 countsByYear W20222469762020 @default.
• W2022246976 countsByYear W20222469762021 @default.
• W2022246976 countsByYear W20222469762022 @default.
• W2022246976 countsByYear W20222469762023 @default.
• W2022246976 crossrefType "journal-article" @default.
• W2022246976 hasAuthorship W2022246976A5025939467 @default.
• W2022246976 hasAuthorship W2022246976A5032202964 @default.
• W2022246976 hasAuthorship W2022246976A5052653055 @default.
• W2022246976 hasBestOaLocation W20222469762 @default.
• W2022246976 hasConcept C105702510 @default.
• W2022246976 hasConcept C113246987 @default.
• W2022246976 hasConcept C140530291 @default.
• W2022246976 hasConcept C153911025 @default.
• W2022246976 hasConcept C169760540 @default.
• W2022246976 hasConcept C202751555 @default.
• W2022246976 hasConcept C2777542381 @default.
• W2022246976 hasConcept C29648211 @default.
• W2022246976 hasConcept C529278444 @default.
• W2022246976 hasConcept C55493867 @default.
• W2022246976 hasConcept C86803240 @default.
• W2022246976 hasConcept C95444343 @default.
• W2022246976 hasConceptScore W2022246976C105702510 @default.
• W2022246976 hasConceptScore W2022246976C113246987 @default.
• W2022246976 hasConceptScore W2022246976C140530291 @default.
• W2022246976 hasConceptScore W2022246976C153911025 @default.
• W2022246976 hasConceptScore W2022246976C169760540 @default.
• W2022246976 hasConceptScore W2022246976C202751555 @default.
• W2022246976 hasConceptScore W2022246976C2777542381 @default.
• W2022246976 hasConceptScore W2022246976C29648211 @default.
• W2022246976 hasConceptScore W2022246976C529278444 @default.
• W2022246976 hasConceptScore W2022246976C55493867 @default.
• W2022246976 hasConceptScore W2022246976C86803240 @default.
• W2022246976 hasConceptScore W2022246976C95444343 @default.
• W2022246976 hasIssue "2" @default.
• W2022246976 hasLocation W20222469761 @default.
• W2022246976 hasLocation W20222469762 @default.

• next