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- W2022247920 abstract "Synopsis Dandruff (pityriasis capitis) is a chronic scalp condition characterized by scaling and sometimes itching and redness. Shampoos containing antifungal agents are used to control the scaling condition. In the present study, two shampoos with different actives are compared in a double‐blind, randomised and bilateral study on 19 subjects. One shampoo contained piroctone olamine (0.75%) combined with salicylic acid (2%) and the other contained zinc pyrithione (1%) as active ingredient. The subjects were treated twice weekly with the shampoos for almost 4 weeks. Before each treatment the degree of dandruff was evaluated. Both shampoos were highly effective in reducing the dandruff. The combination of piroctone olamine and salicylic acid appeared to be slightly more effective than zinc pyrithione in reducing the severity and area affected by the scaling. Résumé L’état pelliculaire pityraisis capitis est une maladie chronique du cuir chevelu, caractérisée par des desquamations et dans certain cas des démangeaisons et des rougeurs. Les shampooings contenant des agents antifongiques sont utilisés pour contrôler l’état du cuir chevelu. Dans cette étude, deux shampooings aux actifs differents sont comparés dans un test bilatéral en double aveugle et au hasard sur 19 sujets. Un des shampooings contient de la piroctone olamine (0,75%) combinée avec de l’acide salicylique (2%). L’autre shampooing contient de la pyrithione zinc (1%) comme actif. Les sujets sont traités avec les shampooings deux fois par semaine pendant quatres semaines. Avant chaque traîtement, le degré de l’état pelliculaire a étéévalué. Les shampooings ont réduit de façon significative l’état pelliculaire dans les deux cas. Toutefois la combinasion piroctone olamine/acide salicylique semble être plus efficace que la pyrithione zinc tant au niveau de la severité de la maladie et de la surface affectée par la desquamation." @default.
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- W2022247920 date "2000-08-01" @default.
- W2022247920 modified "2023-10-16" @default.
- W2022247920 title "The antidandruff efficacy of a shampoo containing piroctone olamine and salicylic acid in comparison to that of a zinc pyrithione shampoo" @default.
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- W2022247920 doi "https://doi.org/10.1046/j.1467-2494.2000.00024.x" @default.
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