FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022248805> ?p ?o ?g. }

• W2022248805 endingPage "488" @default.
• W2022248805 startingPage "483" @default.
• W2022248805 abstract "To define the number of people in Tayside, Scotland (population 349 303) with Type 2 diabetes who use metformin, the incidence of contraindications to its continued use in these people and the proportion that discontinued metformin treatment following the development of a contraindication.Retrospective cohort study of the incidence of contraindications to metformin in all patients with Type 2 diabetes using metformin from January 1993 to June 1995. The contraindications of acute myocardial infarction, cardiac failure, renal impairment and chronic liver disease were identified by: the regional diabetes information system, biochemistry database and hospital admissions database and a database of all encashed community prescriptions.One thousand eight hundred and forty seven subjects (26.3% of those with Type 2 diabetes) redeemed prescriptions for metformin. Of these, 3.5% were admitted with an acute myocardial infarction (71 episodes); 4.2% were admitted with cardiac failure (114 episodes); 21.0% received metformin and loop diuretics for cardiac failure concurrently; 4.8% developed renal impairment; and 2.8% developed chronic liver disease. The development of contraindications rarely resulted in discontinuation of metformin, for example only 17.5% and 25% stopped metformin after admission with acute myocardial infarction and development of renal impairment, respectively. In total, 24.5% of subjects receiving metformin, 6.4% of all people with Type 2 diabetes, had contraindications to its use. There was one episode of lactic acidosis in 4600 patient years.This population-based study shows that 24.5% of patients prescribed metformin have contraindications to its use. Development of contraindications rarely results in discontinuation of metformin therapy. Despite this, lactic acidosis remains rare. Diabet. Med. 18, 483-488 (2001)" @default.
• W2022248805 created "2016-06-24" @default.
• W2022248805 creator A5003477617 @default.
• W2022248805 creator A5034872013 @default.
• W2022248805 creator A5070554877 @default.
• W2022248805 creator A5070741714 @default.
• W2022248805 creator A5074997611 @default.
• W2022248805 date "2001-06-01" @default.
• W2022248805 modified "2023-10-18" @default.
• W2022248805 title "Contraindications to metformin therapy in patients with Type 2 diabetes-a population-based study of adherence to prescribing guidelines" @default.
• W2022248805 cites W1552051186 @default.
• W2022248805 cites W1964423574 @default.
• W2022248805 cites W2000223845 @default.
• W2022248805 cites W2000242491 @default.
• W2022248805 cites W2049554771 @default.
• W2022248805 cites W2051115477 @default.
• W2022248805 cites W2056347227 @default.
• W2022248805 cites W2140090067 @default.
• W2022248805 cites W2160949766 @default.
• W2022248805 cites W2188846692 @default.
• W2022248805 cites W2315982688 @default.
• W2022248805 cites W4236889344 @default.
• W2022248805 cites W4242701763 @default.
• W2022248805 cites W4245367233 @default.
• W2022248805 cites W4247092916 @default.
• W2022248805 cites W4255131986 @default.
• W2022248805 doi "https://doi.org/10.1046/j.1464-5491.2001.00509.x" @default.
• W2022248805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11472468" @default.
• W2022248805 hasPublicationYear "2001" @default.
• W2022248805 type Work @default.
• W2022248805 sameAs 2022248805 @default.
• W2022248805 citedByCount "179" @default.
• W2022248805 countsByYear W20222488052012 @default.
• W2022248805 countsByYear W20222488052013 @default.
• W2022248805 countsByYear W20222488052014 @default.
• W2022248805 countsByYear W20222488052015 @default.
• W2022248805 countsByYear W20222488052016 @default.
• W2022248805 countsByYear W20222488052017 @default.
• W2022248805 countsByYear W20222488052018 @default.
• W2022248805 countsByYear W20222488052019 @default.
• W2022248805 countsByYear W20222488052020 @default.
• W2022248805 countsByYear W20222488052021 @default.
• W2022248805 countsByYear W20222488052022 @default.
• W2022248805 countsByYear W20222488052023 @default.
• W2022248805 crossrefType "journal-article" @default.
• W2022248805 hasAuthorship W2022248805A5003477617 @default.
• W2022248805 hasAuthorship W2022248805A5034872013 @default.
• W2022248805 hasAuthorship W2022248805A5070554877 @default.
• W2022248805 hasAuthorship W2022248805A5070741714 @default.
• W2022248805 hasAuthorship W2022248805A5074997611 @default.
• W2022248805 hasBestOaLocation W20222488051 @default.
• W2022248805 hasConcept C120665830 @default.
• W2022248805 hasConcept C121332964 @default.
• W2022248805 hasConcept C126322002 @default.
• W2022248805 hasConcept C134018914 @default.
• W2022248805 hasConcept C141071460 @default.
• W2022248805 hasConcept C142724271 @default.
• W2022248805 hasConcept C177713679 @default.
• W2022248805 hasConcept C187212893 @default.
• W2022248805 hasConcept C204787440 @default.
• W2022248805 hasConcept C2426938 @default.
• W2022248805 hasConcept C2776494729 @default.
• W2022248805 hasConcept C2777180221 @default.
• W2022248805 hasConcept C2778715236 @default.
• W2022248805 hasConcept C2780317664 @default.
• W2022248805 hasConcept C2780323712 @default.
• W2022248805 hasConcept C2908647359 @default.
• W2022248805 hasConcept C500558357 @default.
• W2022248805 hasConcept C555293320 @default.
• W2022248805 hasConcept C61511704 @default.
• W2022248805 hasConcept C71924100 @default.
• W2022248805 hasConcept C98274493 @default.
• W2022248805 hasConcept C99454951 @default.
• W2022248805 hasConceptScore W2022248805C120665830 @default.
• W2022248805 hasConceptScore W2022248805C121332964 @default.
• W2022248805 hasConceptScore W2022248805C126322002 @default.
• W2022248805 hasConceptScore W2022248805C134018914 @default.
• W2022248805 hasConceptScore W2022248805C141071460 @default.
• W2022248805 hasConceptScore W2022248805C142724271 @default.
• W2022248805 hasConceptScore W2022248805C177713679 @default.
• W2022248805 hasConceptScore W2022248805C187212893 @default.
• W2022248805 hasConceptScore W2022248805C204787440 @default.
• W2022248805 hasConceptScore W2022248805C2426938 @default.
• W2022248805 hasConceptScore W2022248805C2776494729 @default.
• W2022248805 hasConceptScore W2022248805C2777180221 @default.
• W2022248805 hasConceptScore W2022248805C2778715236 @default.
• W2022248805 hasConceptScore W2022248805C2780317664 @default.
• W2022248805 hasConceptScore W2022248805C2780323712 @default.
• W2022248805 hasConceptScore W2022248805C2908647359 @default.
• W2022248805 hasConceptScore W2022248805C500558357 @default.
• W2022248805 hasConceptScore W2022248805C555293320 @default.
• W2022248805 hasConceptScore W2022248805C61511704 @default.
• W2022248805 hasConceptScore W2022248805C71924100 @default.
• W2022248805 hasConceptScore W2022248805C98274493 @default.
• W2022248805 hasConceptScore W2022248805C99454951 @default.
• W2022248805 hasIssue "6" @default.
• W2022248805 hasLocation W20222488051 @default.
• W2022248805 hasLocation W20222488052 @default.

• next