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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022250332> ?p ?o ?g. }

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• W2022250332 abstract "The aim of this randomised trial was to compare the efficacy of bolus versus continuous infusion cisplatin combined with mitomycin C and vindesine (MVP) for chemotherapy-naive patients with stage IIIB–IV non-small cell lung cancer (NSCLC). 97 patients (49 given bolus cisplatin—arm A and 48 given continuous infusion cisplatin—arm B) were evaluable for response. In arm A, 2 patients achieved a complete response (CR), 21 achieved a partial response (PR), whilst in arm B, 14 patients achieved a PR (29%) (P=0.07). Median survival was 8 months in both arms. Myelosuppression was the most frequent and severe toxicity, with a higher incidence of grade 3–4 leucopenia in arm A when compared with arm B (44% versus 25%). In conclusion, there is no advantage for a cisplatin 5 day infusion in the MVP regimen." @default.
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• W2022250332 date "1998-11-01" @default.
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• W2022250332 title "Bolus versus 5-day continuous infusion of cisplatin with mitomycin and vindesine in the treatment of advanced non-small cell lung cancer (NSCLC): a phase III prospective randomised trial of the Italian Oncology Group for Clinical Research (GOIRC)" @default.
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• W2022250332 doi "https://doi.org/10.1016/s0959-8049(98)00231-7" @default.
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