Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022251801> ?p ?o ?g. }
- W2022251801 endingPage "1503" @default.
- W2022251801 startingPage "1496" @default.
- W2022251801 abstract "Studies have suggested that the use of hepatitis C virus (HCV)-positive (HCV+) donor allografts has no impact on survival. However, no studies have examined the effect that HCV+ donor histology has upon recipient and graft survival. We evaluated the clinical outcome and impact of histological features in HCV patients transplanted using HCV+ livers. We reviewed all patients transplanted for HCV at our institution from 1988 to 2004; 39 received HCV+ allografts and 580 received HCV-negative (HCV−) allografts. Survival curves compared graft and patient survival. Each HCV+ allograft was stringently matched to a control of HCV− graft recipients. No significant difference in survival was noted between recipients of HCV+ livers and controls. Patients receiving HCV+ allografts from older donors (age ≥50 yr) had higher rates of graft failure (hazard ratio, 2.74) and death rates (hazard ratio, 2.63) compared to HCV− allograft recipients receiving similarly-aged older donor livers. Matched case-control analysis revealed that recipients of HCV+ allografts had more severe fibrosis post-liver transplantation than recipients of HCV− livers (P = 0.008). More advanced fibrosis was observed in HCV+ grafts from older donors compared to HCV+ grafts from younger donors (P = 0.012). In conclusion, recipients of HCV+ grafts from older donors have higher rates of death and graft failure, and develop more extensive fibrosis than HCV− graft recipients from older donors. Recipients of HCV+ grafts, regardless of donor age, develop more advanced liver fibrosis than recipients of HCV− grafts. Liver Transpl 12:1496-1503, 2006. © 2006 AASLD." @default.
- W2022251801 created "2016-06-24" @default.
- W2022251801 creator A5004762925 @default.
- W2022251801 creator A5022761217 @default.
- W2022251801 creator A5024907781 @default.
- W2022251801 creator A5035293166 @default.
- W2022251801 creator A5043520395 @default.
- W2022251801 creator A5056286011 @default.
- W2022251801 creator A5066214063 @default.
- W2022251801 date "2006-01-01" @default.
- W2022251801 modified "2023-10-15" @default.
- W2022251801 title "Impact of donor age on survival and fibrosis progression in patients with hepatitis C undergoing liver transplantation using HCV+ allografts" @default.
- W2022251801 cites W1966112709 @default.
- W2022251801 cites W1967943339 @default.
- W2022251801 cites W1972408086 @default.
- W2022251801 cites W1974279381 @default.
- W2022251801 cites W1981900811 @default.
- W2022251801 cites W1991378085 @default.
- W2022251801 cites W1992945512 @default.
- W2022251801 cites W2012389069 @default.
- W2022251801 cites W2046742863 @default.
- W2022251801 cites W2065990825 @default.
- W2022251801 cites W2068450514 @default.
- W2022251801 cites W2071974510 @default.
- W2022251801 cites W2074538265 @default.
- W2022251801 cites W2076498524 @default.
- W2022251801 cites W2102675494 @default.
- W2022251801 cites W2103991814 @default.
- W2022251801 cites W2131094305 @default.
- W2022251801 cites W2132290252 @default.
- W2022251801 cites W2136890362 @default.
- W2022251801 cites W2149610087 @default.
- W2022251801 cites W2160029914 @default.
- W2022251801 cites W2162688805 @default.
- W2022251801 doi "https://doi.org/10.1002/lt.20849" @default.
- W2022251801 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16964597" @default.
- W2022251801 hasPublicationYear "2006" @default.
- W2022251801 type Work @default.
- W2022251801 sameAs 2022251801 @default.
- W2022251801 citedByCount "99" @default.
- W2022251801 countsByYear W20222518012012 @default.
- W2022251801 countsByYear W20222518012013 @default.
- W2022251801 countsByYear W20222518012014 @default.
- W2022251801 countsByYear W20222518012015 @default.
- W2022251801 countsByYear W20222518012016 @default.
- W2022251801 countsByYear W20222518012017 @default.
- W2022251801 countsByYear W20222518012018 @default.
- W2022251801 countsByYear W20222518012019 @default.
- W2022251801 countsByYear W20222518012020 @default.
- W2022251801 countsByYear W20222518012021 @default.
- W2022251801 countsByYear W20222518012022 @default.
- W2022251801 countsByYear W20222518012023 @default.
- W2022251801 crossrefType "journal-article" @default.
- W2022251801 hasAuthorship W2022251801A5004762925 @default.
- W2022251801 hasAuthorship W2022251801A5022761217 @default.
- W2022251801 hasAuthorship W2022251801A5024907781 @default.
- W2022251801 hasAuthorship W2022251801A5035293166 @default.
- W2022251801 hasAuthorship W2022251801A5043520395 @default.
- W2022251801 hasAuthorship W2022251801A5056286011 @default.
- W2022251801 hasAuthorship W2022251801A5066214063 @default.
- W2022251801 hasConcept C126322002 @default.
- W2022251801 hasConcept C141071460 @default.
- W2022251801 hasConcept C203014093 @default.
- W2022251801 hasConcept C207103383 @default.
- W2022251801 hasConcept C2522874641 @default.
- W2022251801 hasConcept C2776408679 @default.
- W2022251801 hasConcept C2776455275 @default.
- W2022251801 hasConcept C2779609443 @default.
- W2022251801 hasConcept C2780559512 @default.
- W2022251801 hasConcept C2911091166 @default.
- W2022251801 hasConcept C44249647 @default.
- W2022251801 hasConcept C71924100 @default.
- W2022251801 hasConcept C90924648 @default.
- W2022251801 hasConceptScore W2022251801C126322002 @default.
- W2022251801 hasConceptScore W2022251801C141071460 @default.
- W2022251801 hasConceptScore W2022251801C203014093 @default.
- W2022251801 hasConceptScore W2022251801C207103383 @default.
- W2022251801 hasConceptScore W2022251801C2522874641 @default.
- W2022251801 hasConceptScore W2022251801C2776408679 @default.
- W2022251801 hasConceptScore W2022251801C2776455275 @default.
- W2022251801 hasConceptScore W2022251801C2779609443 @default.
- W2022251801 hasConceptScore W2022251801C2780559512 @default.
- W2022251801 hasConceptScore W2022251801C2911091166 @default.
- W2022251801 hasConceptScore W2022251801C44249647 @default.
- W2022251801 hasConceptScore W2022251801C71924100 @default.
- W2022251801 hasConceptScore W2022251801C90924648 @default.
- W2022251801 hasIssue "10" @default.
- W2022251801 hasLocation W20222518011 @default.
- W2022251801 hasLocation W20222518012 @default.
- W2022251801 hasOpenAccess W2022251801 @default.
- W2022251801 hasPrimaryLocation W20222518011 @default.
- W2022251801 hasRelatedWork W1979664732 @default.
- W2022251801 hasRelatedWork W2047045739 @default.
- W2022251801 hasRelatedWork W2052290779 @default.
- W2022251801 hasRelatedWork W2107508210 @default.
- W2022251801 hasRelatedWork W2117027295 @default.
- W2022251801 hasRelatedWork W2130839534 @default.
- W2022251801 hasRelatedWork W2418235480 @default.