FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022252083> ?p ?o ?g. }

• W2022252083 endingPage "172" @default.
• W2022252083 startingPage "163" @default.
• W2022252083 abstract "Acute coronary syndromes without ST elevation are a major health and economic burden. Treatments such as glycoprotein IIb/IIIa antagonists like tirofiban reduce the risk of complications but the cost impact of these agents including cost offsets of avoiding complications are needed particularly in Europe.We used treatment patterns from the Prospective Registry of Acute Ischemic Syndromes in the UK, risk reductions derived from the PRISM-PLUS trial and cost estimates from the CHKS database to estimate the impact of tirofiban on PRAIS-UK patients with and without complications and subgroups at higher risk of complications. These subgroups (and proportions) were patients: (1) aged 60 or over with abnormal electrocardiograms (58%), (2) with ST depression or bundle branch block on admission (30%) and (3) with ST depression, bundle branch block or MI on admission (37%).Total cost of care in the UK at 6 months for the estimated 87339 acute coronary syndromes admissions annually was pound 213 million, which would increase by pound 33 million (15.7%) if tirofiban were given to all patients, avoiding 2422 complications at a mean cost per event avoided of pound 13388. Among the subgroups, the mean cost per event avoided ranges from pound 10856 for subgroup 1 to pound 5953 for subgroup 3. Treating the latter subgroup, would avoid 1977 events at a cost of pound 12 million (5.5%).The use of tirofiban in the UK to treat acute coronary syndromes patients without ST elevation provides an important therapeutic advantage at modest proportional increase in cost, particularly if targeted to higher risk subgroups as recommended in the European guidelines." @default.
• W2022252083 created "2016-06-24" @default.
• W2022252083 creator A5003409008 @default.
• W2022252083 creator A5025292804 @default.
• W2022252083 creator A5031858128 @default.
• W2022252083 creator A5035559204 @default.
• W2022252083 creator A5037858868 @default.
• W2022252083 creator A5048628555 @default.
• W2022252083 creator A5051943172 @default.
• W2022252083 creator A5086813782 @default.
• W2022252083 date "2003-10-01" @default.
• W2022252083 modified "2023-10-17" @default.
• W2022252083 title "National economic impact of tirofiban for unstable angina and myocardial infarction without ST elevation; example from the United Kingdom" @default.
• W2022252083 cites W1978594418 @default.
• W2022252083 cites W1989995693 @default.
• W2022252083 cites W2012907580 @default.
• W2022252083 cites W2057395242 @default.
• W2022252083 cites W2097258698 @default.
• W2022252083 cites W2127489984 @default.
• W2022252083 cites W2137499117 @default.
• W2022252083 cites W2140435140 @default.
• W2022252083 cites W2157189897 @default.
• W2022252083 cites W2158336299 @default.
• W2022252083 cites W2161356389 @default.
• W2022252083 cites W2330351728 @default.
• W2022252083 cites W2616136614 @default.
• W2022252083 cites W2917470550 @default.
• W2022252083 cites W3155174407 @default.
• W2022252083 cites W78244007 @default.
• W2022252083 doi "https://doi.org/10.1016/s0167-5273(03)00023-8" @default.
• W2022252083 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14559126" @default.
• W2022252083 hasPublicationYear "2003" @default.
• W2022252083 type Work @default.
• W2022252083 sameAs 2022252083 @default.
• W2022252083 citedByCount "8" @default.
• W2022252083 countsByYear W20222520832013 @default.
• W2022252083 countsByYear W20222520832016 @default.
• W2022252083 crossrefType "journal-article" @default.
• W2022252083 hasAuthorship W2022252083A5003409008 @default.
• W2022252083 hasAuthorship W2022252083A5025292804 @default.
• W2022252083 hasAuthorship W2022252083A5031858128 @default.
• W2022252083 hasAuthorship W2022252083A5035559204 @default.
• W2022252083 hasAuthorship W2022252083A5037858868 @default.
• W2022252083 hasAuthorship W2022252083A5048628555 @default.
• W2022252083 hasAuthorship W2022252083A5051943172 @default.
• W2022252083 hasAuthorship W2022252083A5086813782 @default.
• W2022252083 hasConcept C112930515 @default.
• W2022252083 hasConcept C126322002 @default.
• W2022252083 hasConcept C136764020 @default.
• W2022252083 hasConcept C164705383 @default.
• W2022252083 hasConcept C194828623 @default.
• W2022252083 hasConcept C2776291336 @default.
• W2022252083 hasConcept C2776335557 @default.
• W2022252083 hasConcept C2777698277 @default.
• W2022252083 hasConcept C2777785093 @default.
• W2022252083 hasConcept C2780400711 @default.
• W2022252083 hasConcept C2781056559 @default.
• W2022252083 hasConcept C2781350852 @default.
• W2022252083 hasConcept C3019080777 @default.
• W2022252083 hasConcept C41008148 @default.
• W2022252083 hasConcept C44249647 @default.
• W2022252083 hasConcept C500558357 @default.
• W2022252083 hasConcept C71924100 @default.
• W2022252083 hasConceptScore W2022252083C112930515 @default.
• W2022252083 hasConceptScore W2022252083C126322002 @default.
• W2022252083 hasConceptScore W2022252083C136764020 @default.
• W2022252083 hasConceptScore W2022252083C164705383 @default.
• W2022252083 hasConceptScore W2022252083C194828623 @default.
• W2022252083 hasConceptScore W2022252083C2776291336 @default.
• W2022252083 hasConceptScore W2022252083C2776335557 @default.
• W2022252083 hasConceptScore W2022252083C2777698277 @default.
• W2022252083 hasConceptScore W2022252083C2777785093 @default.
• W2022252083 hasConceptScore W2022252083C2780400711 @default.
• W2022252083 hasConceptScore W2022252083C2781056559 @default.
• W2022252083 hasConceptScore W2022252083C2781350852 @default.
• W2022252083 hasConceptScore W2022252083C3019080777 @default.
• W2022252083 hasConceptScore W2022252083C41008148 @default.
• W2022252083 hasConceptScore W2022252083C44249647 @default.
• W2022252083 hasConceptScore W2022252083C500558357 @default.
• W2022252083 hasConceptScore W2022252083C71924100 @default.
• W2022252083 hasIssue "2-3" @default.
• W2022252083 hasLocation W20222520831 @default.
• W2022252083 hasLocation W20222520832 @default.
• W2022252083 hasOpenAccess W2022252083 @default.
• W2022252083 hasPrimaryLocation W20222520831 @default.
• W2022252083 hasRelatedWork W1967164915 @default.
• W2022252083 hasRelatedWork W2049397185 @default.
• W2022252083 hasRelatedWork W2065378290 @default.
• W2022252083 hasRelatedWork W2127302333 @default.
• W2022252083 hasRelatedWork W2142714103 @default.
• W2022252083 hasRelatedWork W2163292105 @default.
• W2022252083 hasRelatedWork W2319398042 @default.
• W2022252083 hasRelatedWork W4237226406 @default.
• W2022252083 hasRelatedWork W4251138038 @default.
• W2022252083 hasRelatedWork W4255122426 @default.
• W2022252083 hasVolume "91" @default.
• W2022252083 isParatext "false" @default.
• W2022252083 isRetracted "false" @default.

• next