Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022252206> ?p ?o ?g. }
- W2022252206 endingPage "3406" @default.
- W2022252206 startingPage "3395" @default.
- W2022252206 abstract "Our study goals to investigate the anti-arthritic potential of Salix nigra bark methanol extract (SNME) against both inflammation and oxidative stress in the collagen-induced arthritis (CIA) rat model. Results showed that SNME exhibited maximum scavenging activity against superoxide, hypochlorous acid and hydrogen peroxide radicals along with the suppression of lipid peroxidation. Female wistar rats were immunized with porcine type II collagen and treated with SNME (100 mg/kg body weight) for 15 days starting on day 20. SNME significantly inhibited the paw swelling and arthritic score; exhibited maximum CIA inhibition of 93.7% by the end of the experimental period. Administration of SNME to arthritic rats significantly improved the histological findings in joints as evident by reduced infiltration of polymorphonuclear cells and smooth synovial lining. Roentgenograms of tibiotarsal joints of both SNME and indomethacin-treated rats showed protection against osteophyte formation, soft tissue swelling and bone resorption. Furthermore, levels of inflammatory mediators (nitric oxide, TNF-α, IL-1β, IL-6) measured in both plasma and joint exudates were significantly reduced by SNME treatment. Increased oxidative stress observed in the arthritic animals was also found to be significantly restored in SNME- treated rats. Taken together, our studies clearly indicate the potential of S. nigra as an anti-arthritic agent." @default.
- W2022252206 created "2016-06-24" @default.
- W2022252206 creator A5015783767 @default.
- W2022252206 creator A5021065960 @default.
- W2022252206 creator A5043443002 @default.
- W2022252206 creator A5088459668 @default.
- W2022252206 date "2011-12-01" @default.
- W2022252206 modified "2023-10-16" @default.
- W2022252206 title "Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress" @default.
- W2022252206 cites W106125267 @default.
- W2022252206 cites W1541495845 @default.
- W2022252206 cites W1584738578 @default.
- W2022252206 cites W1647598887 @default.
- W2022252206 cites W1965592816 @default.
- W2022252206 cites W1969775578 @default.
- W2022252206 cites W1971925060 @default.
- W2022252206 cites W1980365570 @default.
- W2022252206 cites W1990541922 @default.
- W2022252206 cites W2001328408 @default.
- W2022252206 cites W2001789586 @default.
- W2022252206 cites W2002344557 @default.
- W2022252206 cites W2009111718 @default.
- W2022252206 cites W2012579765 @default.
- W2022252206 cites W2014856474 @default.
- W2022252206 cites W2016469284 @default.
- W2022252206 cites W2017902830 @default.
- W2022252206 cites W2020470017 @default.
- W2022252206 cites W2021812533 @default.
- W2022252206 cites W2027954338 @default.
- W2022252206 cites W2040678265 @default.
- W2022252206 cites W2044924856 @default.
- W2022252206 cites W2046750894 @default.
- W2022252206 cites W2047076468 @default.
- W2022252206 cites W2055632372 @default.
- W2022252206 cites W2056032834 @default.
- W2022252206 cites W2058096481 @default.
- W2022252206 cites W2058314241 @default.
- W2022252206 cites W2064212406 @default.
- W2022252206 cites W2064303583 @default.
- W2022252206 cites W2077013120 @default.
- W2022252206 cites W2085465824 @default.
- W2022252206 cites W2088793125 @default.
- W2022252206 cites W2090104922 @default.
- W2022252206 cites W2105261402 @default.
- W2022252206 cites W2121793916 @default.
- W2022252206 cites W2124638673 @default.
- W2022252206 cites W2126896697 @default.
- W2022252206 cites W2138132897 @default.
- W2022252206 cites W2140315299 @default.
- W2022252206 cites W2142561107 @default.
- W2022252206 cites W2146163019 @default.
- W2022252206 cites W2153081626 @default.
- W2022252206 cites W4252911190 @default.
- W2022252206 doi "https://doi.org/10.1016/j.fct.2011.08.013" @default.
- W2022252206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21983485" @default.
- W2022252206 hasPublicationYear "2011" @default.
- W2022252206 type Work @default.
- W2022252206 sameAs 2022252206 @default.
- W2022252206 citedByCount "46" @default.
- W2022252206 countsByYear W20222522062012 @default.
- W2022252206 countsByYear W20222522062013 @default.
- W2022252206 countsByYear W20222522062014 @default.
- W2022252206 countsByYear W20222522062015 @default.
- W2022252206 countsByYear W20222522062016 @default.
- W2022252206 countsByYear W20222522062017 @default.
- W2022252206 countsByYear W20222522062018 @default.
- W2022252206 countsByYear W20222522062019 @default.
- W2022252206 countsByYear W20222522062020 @default.
- W2022252206 countsByYear W20222522062021 @default.
- W2022252206 countsByYear W20222522062022 @default.
- W2022252206 countsByYear W20222522062023 @default.
- W2022252206 crossrefType "journal-article" @default.
- W2022252206 hasAuthorship W2022252206A5015783767 @default.
- W2022252206 hasAuthorship W2022252206A5021065960 @default.
- W2022252206 hasAuthorship W2022252206A5043443002 @default.
- W2022252206 hasAuthorship W2022252206A5088459668 @default.
- W2022252206 hasConcept C126322002 @default.
- W2022252206 hasConcept C134018914 @default.
- W2022252206 hasConcept C185592680 @default.
- W2022252206 hasConcept C203014093 @default.
- W2022252206 hasConcept C2776151105 @default.
- W2022252206 hasConcept C2776914184 @default.
- W2022252206 hasConcept C2777077863 @default.
- W2022252206 hasConcept C2778401633 @default.
- W2022252206 hasConcept C2780829032 @default.
- W2022252206 hasConcept C55493867 @default.
- W2022252206 hasConcept C71924100 @default.
- W2022252206 hasConcept C98274493 @default.
- W2022252206 hasConceptScore W2022252206C126322002 @default.
- W2022252206 hasConceptScore W2022252206C134018914 @default.
- W2022252206 hasConceptScore W2022252206C185592680 @default.
- W2022252206 hasConceptScore W2022252206C203014093 @default.
- W2022252206 hasConceptScore W2022252206C2776151105 @default.
- W2022252206 hasConceptScore W2022252206C2776914184 @default.
- W2022252206 hasConceptScore W2022252206C2777077863 @default.
- W2022252206 hasConceptScore W2022252206C2778401633 @default.
- W2022252206 hasConceptScore W2022252206C2780829032 @default.
- W2022252206 hasConceptScore W2022252206C55493867 @default.