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- W2022253681 abstract "Actions of thyrotrophin-releasing hormone (TRH) have generally been confined to the central nervous system (CNS). We have studied the effect of increasing doses of TRH i.v. (8, 40, 200 and 1000 μg/h) on pentagastrin-stimulated gastric secretion in ten normal individuals. All doses caused stepwise inhibition of gastric juice (volume), acid and pepsin output. When employing the largest dose of i.v. TRH (1000 μg/h) the inhibition was 44% for gastric volume, 51% for acid output and 57% for pepsin output. This study shows that TRH inhibits gastric secretion, and indicates that TRH has actions outside the CNS in man." @default.
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- W2022253681 date "1979-03-01" @default.
- W2022253681 modified "2023-10-17" @default.
- W2022253681 title "THYROTROPHIN-RELEASING HORMONE INHIBITS THE PENTAGASTRIN STIMULATED GASTRIC SECRETION IN MAN. A DOSE RESPONSE STUDY" @default.
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- W2022253681 doi "https://doi.org/10.1111/j.1365-2265.1979.tb02082.x" @default.
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