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- W2022255673 abstract "Human C21orf63 is a type-1 transmembrane protein of hitherto unknown function, with two repeats of putative ‘galactose-binding lectin domains'. By using glycan microarray analysis and other assays, we found that human C21orf63 interacts with heparin and to a lesser extent with heparan sulphate. The C-terminal galactose-binding lectin domain of C21orf63 is necessary for heparin binding. The inability of other human proteins with galactose-binding lectin domains to interact with heparin suggests that heparin binding is a unique property of C21orf63. Results of real-time polymerase chain reaction and tissue immunostaining imply that C21orf63 is expressed on epithelia of various human tissues." @default.
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- W2022255673 date "2009-05-26" @default.
- W2022255673 modified "2023-09-23" @default.
- W2022255673 title "Human C21orf63 is a Heparin-binding Protein" @default.
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- W2022255673 doi "https://doi.org/10.1093/jb/mvp079" @default.
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