FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022267672> ?p ?o ?g. }

• W2022267672 endingPage "27" @default.
• W2022267672 startingPage "13" @default.
• W2022267672 abstract "Nucleosome Assembly Protein 1 (NAP1) is a highly conserved histone chaperone protein suspected to be involved in the dynamical regulation of the histone H2A-H2B hetero-dimer. However, the exact mechanism by which NAP1-like proteins act is currently unknown. In this work, we characterized the biochemical properties of two human NAP1-like proteins, hNAP1L1 and hNAP1L4, including a previously uncharacterized subtype, with the aim of determining their exact mechanistic role. Both hNAP1L1 and hNAP1L4 were found to be localized mainly to the cytoplasm and a minor population of them was suggested to be in the nucleus. Biochemical analyses demonstrated that both hNAP1L1 and hNAP1L4 mediated nucleosome formation. In addition, hNAP1L1 was shown to possess a significantly greater nucleosome disassembly activity than hNAP1L4, suggesting that hNAP1L1 and hNAP1L4 may play distinct roles in the regulation of histone dynamics. Building upon this initial discovery we also found that histone H2A-H2B and various histone H2A variants-H2B dimers were found to associate with both hNAP1L1 and hNAP1L4 in cell extracts. These results suggest that human NAP1-like proteins play overlapping roles in transport and deposition of histone H2A-H2B or H2A variants-H2B dimers on chromatin and nonoverlapping roles in nucleosome disassembly." @default.
• W2022267672 created "2016-06-24" @default.
• W2022267672 creator A5027895210 @default.
• W2022267672 creator A5028944524 @default.
• W2022267672 creator A5050987285 @default.
• W2022267672 date "2010-01-01" @default.
• W2022267672 modified "2023-09-25" @default.
• W2022267672 title "Functional characterization of human nucleosome assembly protein 1-like proteins as histone chaperones" @default.
• W2022267672 cites W1512281455 @default.
• W2022267672 cites W1523954091 @default.
• W2022267672 cites W1554851690 @default.
• W2022267672 cites W1612183828 @default.
• W2022267672 cites W1876643910 @default.
• W2022267672 cites W1924576234 @default.
• W2022267672 cites W1970638451 @default.
• W2022267672 cites W1978569157 @default.
• W2022267672 cites W1988997227 @default.
• W2022267672 cites W1989406431 @default.
• W2022267672 cites W1993243592 @default.
• W2022267672 cites W1994577866 @default.
• W2022267672 cites W2004225662 @default.
• W2022267672 cites W2012092938 @default.
• W2022267672 cites W2019349381 @default.
• W2022267672 cites W2020763705 @default.
• W2022267672 cites W2029388127 @default.
• W2022267672 cites W2029394419 @default.
• W2022267672 cites W2040171181 @default.
• W2022267672 cites W2041356725 @default.
• W2022267672 cites W2048257585 @default.
• W2022267672 cites W2052540561 @default.
• W2022267672 cites W2053289821 @default.
• W2022267672 cites W2055407574 @default.
• W2022267672 cites W2063295516 @default.
• W2022267672 cites W2063516501 @default.
• W2022267672 cites W2064104725 @default.
• W2022267672 cites W2065994062 @default.
• W2022267672 cites W2069792902 @default.
• W2022267672 cites W2083069127 @default.
• W2022267672 cites W2083679421 @default.
• W2022267672 cites W2088641994 @default.
• W2022267672 cites W2100363234 @default.
• W2022267672 cites W2116015519 @default.
• W2022267672 cites W2118169279 @default.
• W2022267672 cites W2122062914 @default.
• W2022267672 cites W2127316404 @default.
• W2022267672 cites W2143845633 @default.
• W2022267672 cites W2145130928 @default.
• W2022267672 cites W2165521391 @default.
• W2022267672 cites W2166335680 @default.
• W2022267672 cites W339734295 @default.
• W2022267672 doi "https://doi.org/10.1111/j.1365-2443.2009.01361.x" @default.
• W2022267672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20002496" @default.
• W2022267672 hasPublicationYear "2010" @default.
• W2022267672 type Work @default.
• W2022267672 sameAs 2022267672 @default.
• W2022267672 citedByCount "70" @default.
• W2022267672 countsByYear W20222676722012 @default.
• W2022267672 countsByYear W20222676722013 @default.
• W2022267672 countsByYear W20222676722014 @default.
• W2022267672 countsByYear W20222676722015 @default.
• W2022267672 countsByYear W20222676722016 @default.
• W2022267672 countsByYear W20222676722017 @default.
• W2022267672 countsByYear W20222676722018 @default.
• W2022267672 countsByYear W20222676722019 @default.
• W2022267672 countsByYear W20222676722020 @default.
• W2022267672 countsByYear W20222676722021 @default.
• W2022267672 countsByYear W20222676722022 @default.
• W2022267672 countsByYear W20222676722023 @default.
• W2022267672 crossrefType "journal-article" @default.
• W2022267672 hasAuthorship W2022267672A5027895210 @default.
• W2022267672 hasAuthorship W2022267672A5028944524 @default.
• W2022267672 hasAuthorship W2022267672A5050987285 @default.
• W2022267672 hasBestOaLocation W20222676721 @default.
• W2022267672 hasConcept C10058791 @default.
• W2022267672 hasConcept C101152365 @default.
• W2022267672 hasConcept C142724271 @default.
• W2022267672 hasConcept C164974683 @default.
• W2022267672 hasConcept C2775962898 @default.
• W2022267672 hasConcept C2779320353 @default.
• W2022267672 hasConcept C54355233 @default.
• W2022267672 hasConcept C552990157 @default.
• W2022267672 hasConcept C56428682 @default.
• W2022267672 hasConcept C64927066 @default.
• W2022267672 hasConcept C71924100 @default.
• W2022267672 hasConcept C83640560 @default.
• W2022267672 hasConcept C84772758 @default.
• W2022267672 hasConcept C86803240 @default.
• W2022267672 hasConcept C95444343 @default.
• W2022267672 hasConceptScore W2022267672C10058791 @default.
• W2022267672 hasConceptScore W2022267672C101152365 @default.
• W2022267672 hasConceptScore W2022267672C142724271 @default.
• W2022267672 hasConceptScore W2022267672C164974683 @default.
• W2022267672 hasConceptScore W2022267672C2775962898 @default.
• W2022267672 hasConceptScore W2022267672C2779320353 @default.
• W2022267672 hasConceptScore W2022267672C54355233 @default.
• W2022267672 hasConceptScore W2022267672C552990157 @default.
• W2022267672 hasConceptScore W2022267672C56428682 @default.
• W2022267672 hasConceptScore W2022267672C64927066 @default.

• next