Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022267927> ?p ?o ?g. }
- W2022267927 endingPage "205" @default.
- W2022267927 startingPage "196" @default.
- W2022267927 abstract "Hydrogen sulfide (H2S) is an endogenously generated gas that can also be administered exogenously. It modulates physiological functions and has reported cytoprotective effects. To evaluate a possible antioxidant role, we investigated the reactivity of hydrogen sulfide with several one- and two-electron oxidants. The rate constant of the direct reaction with peroxynitrite was (4.8 ± 1.4) × 103 M− 1 s− 1 (pH 7.4, 37°C). At low hydrogen sulfide concentrations, oxidation by peroxynitrite led to oxygen consumption, consistent with a one-electron oxidation that initiated a radical chain reaction. Accordingly, pulse radiolysis studies indicated that hydrogen sulfide reacted with nitrogen dioxide at (3.0 ± 0.3) × 106 M− 1 s− 1 at pH 6 and (1.2 ± 0.1) × 107 M− 1 s− 1 at pH 7.5 (25 °C). The reactions of hydrogen sulfide with hydrogen peroxide, hypochlorite, and taurine chloramine had rate constants of 0.73 ± 0.03, (8 ± 3) × 107, and 303 ± 27 M− 1 s− 1, respectively (pH 7.4, 37 °C). The reactivity of hydrogen sulfide was compared to that of low-molecular-weight thiols such as cysteine and glutathione. Considering the low tissue concentrations of endogenous hydrogen sulfide, direct reactions with oxidants probably cannot completely account for its protective effects." @default.
- W2022267927 created "2016-06-24" @default.
- W2022267927 creator A5010572858 @default.
- W2022267927 creator A5030681650 @default.
- W2022267927 creator A5033455586 @default.
- W2022267927 creator A5035221413 @default.
- W2022267927 creator A5037114307 @default.
- W2022267927 creator A5038220750 @default.
- W2022267927 creator A5046231280 @default.
- W2022267927 creator A5046252340 @default.
- W2022267927 creator A5059908114 @default.
- W2022267927 creator A5069900283 @default.
- W2022267927 creator A5073926538 @default.
- W2022267927 creator A5085479621 @default.
- W2022267927 date "2011-01-01" @default.
- W2022267927 modified "2023-10-18" @default.
- W2022267927 title "Reactivity of hydrogen sulfide with peroxynitrite and other oxidants of biological interest" @default.
- W2022267927 cites W1500094754 @default.
- W2022267927 cites W1510914671 @default.
- W2022267927 cites W1552595500 @default.
- W2022267927 cites W1587532579 @default.
- W2022267927 cites W1602425415 @default.
- W2022267927 cites W1761291408 @default.
- W2022267927 cites W1803620352 @default.
- W2022267927 cites W1952402412 @default.
- W2022267927 cites W1964287788 @default.
- W2022267927 cites W1967162316 @default.
- W2022267927 cites W1972880155 @default.
- W2022267927 cites W1973591040 @default.
- W2022267927 cites W1981017810 @default.
- W2022267927 cites W1984750832 @default.
- W2022267927 cites W1986619660 @default.
- W2022267927 cites W1989239022 @default.
- W2022267927 cites W1991375427 @default.
- W2022267927 cites W1992096297 @default.
- W2022267927 cites W1994228161 @default.
- W2022267927 cites W1995323993 @default.
- W2022267927 cites W1995340021 @default.
- W2022267927 cites W1996859289 @default.
- W2022267927 cites W2006263357 @default.
- W2022267927 cites W2012634726 @default.
- W2022267927 cites W2014668548 @default.
- W2022267927 cites W2015004067 @default.
- W2022267927 cites W2015208030 @default.
- W2022267927 cites W2015407072 @default.
- W2022267927 cites W2016901103 @default.
- W2022267927 cites W2020770681 @default.
- W2022267927 cites W2022377100 @default.
- W2022267927 cites W2029326990 @default.
- W2022267927 cites W2037083980 @default.
- W2022267927 cites W2038640502 @default.
- W2022267927 cites W2040447429 @default.
- W2022267927 cites W2042314204 @default.
- W2022267927 cites W2042745831 @default.
- W2022267927 cites W2045745420 @default.
- W2022267927 cites W2045910150 @default.
- W2022267927 cites W2054064167 @default.
- W2022267927 cites W2054567864 @default.
- W2022267927 cites W2055406074 @default.
- W2022267927 cites W2055678604 @default.
- W2022267927 cites W2056840435 @default.
- W2022267927 cites W2058013605 @default.
- W2022267927 cites W2059311343 @default.
- W2022267927 cites W2060121377 @default.
- W2022267927 cites W2063207603 @default.
- W2022267927 cites W2064211719 @default.
- W2022267927 cites W2067939107 @default.
- W2022267927 cites W2070213990 @default.
- W2022267927 cites W2070585872 @default.
- W2022267927 cites W2075785716 @default.
- W2022267927 cites W2078672958 @default.
- W2022267927 cites W2078739145 @default.
- W2022267927 cites W2079636467 @default.
- W2022267927 cites W2086676999 @default.
- W2022267927 cites W2109458478 @default.
- W2022267927 cites W2117170204 @default.
- W2022267927 cites W2141610173 @default.
- W2022267927 cites W2159213474 @default.
- W2022267927 cites W2160081886 @default.
- W2022267927 cites W2161123678 @default.
- W2022267927 cites W2169746496 @default.
- W2022267927 cites W222712338 @default.
- W2022267927 cites W2314530439 @default.
- W2022267927 cites W2323169633 @default.
- W2022267927 cites W2326787503 @default.
- W2022267927 cites W2398144103 @default.
- W2022267927 cites W25724041 @default.
- W2022267927 cites W4248869889 @default.
- W2022267927 cites W70949530 @default.
- W2022267927 cites W989016558 @default.
- W2022267927 doi "https://doi.org/10.1016/j.freeradbiomed.2010.10.705" @default.
- W2022267927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21034811" @default.
- W2022267927 hasPublicationYear "2011" @default.
- W2022267927 type Work @default.
- W2022267927 sameAs 2022267927 @default.
- W2022267927 citedByCount "187" @default.
- W2022267927 countsByYear W20222679272012 @default.
- W2022267927 countsByYear W20222679272013 @default.