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- W2022268487 abstract "Rats were given daily 1-hr sessions in photocell cages until baseline locomotion stabilized. d-Amphetamine 0.5–2.0 mg/kg p.o. significantly increased locomotion. Chlorpromazine 2.5–20 mg/kg p.o. and pentobarbital 5.0–20 mg/kg p.o. significantly decreased locomotion. N = 4 per drug. Results demonstrate the appropriateness of using chronic single subjects to assess the effects of drugs on locomotion. An attempt to generate cumulative dose-effect curves in rats run once a week was less successful because of intrasubject variability. The method could also be used for multiple drug studies in lesioned or cannulated preparations." @default.
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- W2022268487 date "1989-01-01" @default.
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- W2022268487 title "Single-Subject design for locomotor activity" @default.
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