Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022274614> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2022274614 endingPage "S41" @default.
- W2022274614 startingPage "S41" @default.
- W2022274614 abstract "Lupus nephritis (LN) is a serious manifestation of systemic lupus erythematosus (SLE). Clinical renal involvement is present in about two-thirds of lupus patients and more patients would have morphologic evidence of renal disease without clinical manifestations.To investigate serum anti-nucleosome antibodies role as a biomarker for renal affection in lupus patients with insignificant proteinuria.Twenty-four lupus patients with proteinuria <500 mg/d (group-A), 30 patients with established lupus nephritis (group-B) and 15 controls were included. Systemic lupus erythematosis disease activity index (SLEDAI), anti-nucleosome, anti-dsDNA antibodies and renal biopsy were assessed in all patients.Serum anti-nucleosome antibodies were significantly higher in all lupus patients than control (P < 0.001) and showed significant positive correlation with SLEDAI score. SLE patients with positive anti-dsDNA antibody had more active disease by SLEDAI and higher levels of anti-nucleosome antibodies than those with negative anti-dsDNA antibodies. In both studied groups, serum anti-nucleosome antibodies were significantly higher in patients with class II LN than the control and in class III LN than in class II LN (P < 0.001). Yet, in both groups, anti-nucleosome was not useful in differentiating active from chronic renal affection.Serum levels of anti-nucleosome antibodies are associated with active lupus disease and correlate with the degree of renal affection. In patients with insignificant proteinuria, serum levels of anti-nucleosome antibodies were elevated and were related to the degree of renal affection. Anti-nucleosome antibodies may be used as a surrogate marker for early renal affection in lupus patients with insignificant proteinuria." @default.
- W2022274614 created "2016-06-24" @default.
- W2022274614 creator A5012529302 @default.
- W2022274614 creator A5037322116 @default.
- W2022274614 creator A5041611661 @default.
- W2022274614 creator A5043576898 @default.
- W2022274614 creator A5046991530 @default.
- W2022274614 creator A5051380594 @default.
- W2022274614 creator A5057591920 @default.
- W2022274614 date "2014-11-01" @default.
- W2022274614 modified "2023-09-27" @default.
- W2022274614 title "Lupus nephritis in South Indian tamil monocentric cohort: Association between clinical and autoantibody expression" @default.
- W2022274614 doi "https://doi.org/10.1016/j.injr.2014.10.122" @default.
- W2022274614 hasPublicationYear "2014" @default.
- W2022274614 type Work @default.
- W2022274614 sameAs 2022274614 @default.
- W2022274614 citedByCount "0" @default.
- W2022274614 crossrefType "journal-article" @default.
- W2022274614 hasAuthorship W2022274614A5012529302 @default.
- W2022274614 hasAuthorship W2022274614A5037322116 @default.
- W2022274614 hasAuthorship W2022274614A5041611661 @default.
- W2022274614 hasAuthorship W2022274614A5043576898 @default.
- W2022274614 hasAuthorship W2022274614A5046991530 @default.
- W2022274614 hasAuthorship W2022274614A5051380594 @default.
- W2022274614 hasAuthorship W2022274614A5057591920 @default.
- W2022274614 hasBestOaLocation W20222746141 @default.
- W2022274614 hasConcept C126322002 @default.
- W2022274614 hasConcept C159654299 @default.
- W2022274614 hasConcept C163764329 @default.
- W2022274614 hasConcept C203014093 @default.
- W2022274614 hasConcept C2776912625 @default.
- W2022274614 hasConcept C2779134260 @default.
- W2022274614 hasConcept C2779561371 @default.
- W2022274614 hasConcept C2779912601 @default.
- W2022274614 hasConcept C2780091579 @default.
- W2022274614 hasConcept C2780380361 @default.
- W2022274614 hasConcept C71924100 @default.
- W2022274614 hasConcept C90924648 @default.
- W2022274614 hasConceptScore W2022274614C126322002 @default.
- W2022274614 hasConceptScore W2022274614C159654299 @default.
- W2022274614 hasConceptScore W2022274614C163764329 @default.
- W2022274614 hasConceptScore W2022274614C203014093 @default.
- W2022274614 hasConceptScore W2022274614C2776912625 @default.
- W2022274614 hasConceptScore W2022274614C2779134260 @default.
- W2022274614 hasConceptScore W2022274614C2779561371 @default.
- W2022274614 hasConceptScore W2022274614C2779912601 @default.
- W2022274614 hasConceptScore W2022274614C2780091579 @default.
- W2022274614 hasConceptScore W2022274614C2780380361 @default.
- W2022274614 hasConceptScore W2022274614C71924100 @default.
- W2022274614 hasConceptScore W2022274614C90924648 @default.
- W2022274614 hasLocation W20222746141 @default.
- W2022274614 hasOpenAccess W2022274614 @default.
- W2022274614 hasPrimaryLocation W20222746141 @default.
- W2022274614 hasRelatedWork W1452338814 @default.
- W2022274614 hasRelatedWork W1531212004 @default.
- W2022274614 hasRelatedWork W1896534392 @default.
- W2022274614 hasRelatedWork W1987053899 @default.
- W2022274614 hasRelatedWork W2001903020 @default.
- W2022274614 hasRelatedWork W2520396717 @default.
- W2022274614 hasRelatedWork W2524371664 @default.
- W2022274614 hasRelatedWork W2962616530 @default.
- W2022274614 hasRelatedWork W4205932495 @default.
- W2022274614 hasRelatedWork W4313386619 @default.
- W2022274614 hasVolume "9" @default.
- W2022274614 isParatext "false" @default.
- W2022274614 isRetracted "false" @default.
- W2022274614 magId "2022274614" @default.
- W2022274614 workType "article" @default.