FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022277266> ?p ?o ?g. }

• W2022277266 endingPage "325" @default.
• W2022277266 startingPage "319" @default.
• W2022277266 abstract "Spindle cell melanoma is a rare and distinctive variant of malignant melanoma that is composed of spindled neoplastic cells and includes desmoplastic and neurotropic melanoma. The lack of expression of several melanoma markers may result in a delayed or wrong diagnosis. In this study, we have analyzed in detail the phenotype of the tumor cells in 9 spindle cell melanomas on both paraffin-embedded and frozen material, using melanocytic, neural, and mesenchymal markers. The neoplastic cells expressed the melanocytic markers S-100, Mel-CAM, and NKIC3, but lacked gp100 and Melan-A; tyrosinase and c-Kit were expressed in 2 of 7 cases. Most cases expressed the neural markers p75-nerve growth factor receptor, neural cell adhesion molecule, and NSE. All cases expressed vimentin but lacked the mesenchymal markers CD34 and alpha-smooth muscle actin. Remarkably, all spindle cell melanomas strongly and diffusely expressed the fibroblastic markers Thy1 (CD90) and aminopeptidase N (CD13) and variably expressed the enzyme prolyl-4-hydroxylase, involved in procollagen formation. The coexpression of melanocytic, neural, and fibroblastic markers suggests bidirectional differentiation of neoplastic melanocytes toward (myo)fibroblasts and Schwann cells, a feature that was confirmed by electron microscopy. Furthermore, the lack of CD90 and CD13 staining in a wide range of melanocytic lesions suggests specificity of these markers for spindle cell melanoma." @default.
• W2022277266 created "2016-06-24" @default.
• W2022277266 creator A5000458951 @default.
• W2022277266 creator A5037313267 @default.
• W2022277266 creator A5065825489 @default.
• W2022277266 creator A5086784384 @default.
• W2022277266 date "2003-12-01" @default.
• W2022277266 modified "2023-10-18" @default.
• W2022277266 title "New Phenotypical and Ultrastructural Findings in Spindle Cell (Desmoplastic/Neurotropic) Melanoma" @default.
• W2022277266 cites W1968780289 @default.
• W2022277266 cites W1968858321 @default.
• W2022277266 cites W1969662781 @default.
• W2022277266 cites W1971185405 @default.
• W2022277266 cites W1976581939 @default.
• W2022277266 cites W1997550023 @default.
• W2022277266 cites W2003489154 @default.
• W2022277266 cites W2024444879 @default.
• W2022277266 cites W2031841201 @default.
• W2022277266 cites W2034438862 @default.
• W2022277266 cites W203965711 @default.
• W2022277266 cites W2043949832 @default.
• W2022277266 cites W2060046338 @default.
• W2022277266 cites W2064185923 @default.
• W2022277266 cites W2069005529 @default.
• W2022277266 cites W2069523187 @default.
• W2022277266 cites W2080512292 @default.
• W2022277266 cites W2082351367 @default.
• W2022277266 cites W2085109260 @default.
• W2022277266 cites W2086279386 @default.
• W2022277266 cites W2091630371 @default.
• W2022277266 cites W2093446458 @default.
• W2022277266 cites W2099246728 @default.
• W2022277266 cites W2156371395 @default.
• W2022277266 cites W2167217100 @default.
• W2022277266 cites W2316741937 @default.
• W2022277266 cites W2330680673 @default.
• W2022277266 cites W2765706768 @default.
• W2022277266 cites W4322700127 @default.
• W2022277266 doi "https://doi.org/10.1097/00129039-200312000-00007" @default.
• W2022277266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14663357" @default.
• W2022277266 hasPublicationYear "2003" @default.
• W2022277266 type Work @default.
• W2022277266 sameAs 2022277266 @default.
• W2022277266 citedByCount "47" @default.
• W2022277266 countsByYear W20222772662012 @default.
• W2022277266 countsByYear W20222772662013 @default.
• W2022277266 countsByYear W20222772662014 @default.
• W2022277266 countsByYear W20222772662018 @default.
• W2022277266 countsByYear W20222772662022 @default.
• W2022277266 countsByYear W20222772662023 @default.
• W2022277266 crossrefType "journal-article" @default.
• W2022277266 hasAuthorship W2022277266A5000458951 @default.
• W2022277266 hasAuthorship W2022277266A5037313267 @default.
• W2022277266 hasAuthorship W2022277266A5065825489 @default.
• W2022277266 hasAuthorship W2022277266A5086784384 @default.
• W2022277266 hasConcept C10205521 @default.
• W2022277266 hasConcept C116716535 @default.
• W2022277266 hasConcept C122871604 @default.
• W2022277266 hasConcept C126749454 @default.
• W2022277266 hasConcept C136302470 @default.
• W2022277266 hasConcept C142724271 @default.
• W2022277266 hasConcept C147447768 @default.
• W2022277266 hasConcept C1491633281 @default.
• W2022277266 hasConcept C196843134 @default.
• W2022277266 hasConcept C198826908 @default.
• W2022277266 hasConcept C204232928 @default.
• W2022277266 hasConcept C2777658100 @default.
• W2022277266 hasConcept C28328180 @default.
• W2022277266 hasConcept C502942594 @default.
• W2022277266 hasConcept C54355233 @default.
• W2022277266 hasConcept C71924100 @default.
• W2022277266 hasConcept C85789140 @default.
• W2022277266 hasConcept C86803240 @default.
• W2022277266 hasConcept C95444343 @default.
• W2022277266 hasConceptScore W2022277266C10205521 @default.
• W2022277266 hasConceptScore W2022277266C116716535 @default.
• W2022277266 hasConceptScore W2022277266C122871604 @default.
• W2022277266 hasConceptScore W2022277266C126749454 @default.
• W2022277266 hasConceptScore W2022277266C136302470 @default.
• W2022277266 hasConceptScore W2022277266C142724271 @default.
• W2022277266 hasConceptScore W2022277266C147447768 @default.
• W2022277266 hasConceptScore W2022277266C1491633281 @default.
• W2022277266 hasConceptScore W2022277266C196843134 @default.
• W2022277266 hasConceptScore W2022277266C198826908 @default.
• W2022277266 hasConceptScore W2022277266C204232928 @default.
• W2022277266 hasConceptScore W2022277266C2777658100 @default.
• W2022277266 hasConceptScore W2022277266C28328180 @default.
• W2022277266 hasConceptScore W2022277266C502942594 @default.
• W2022277266 hasConceptScore W2022277266C54355233 @default.
• W2022277266 hasConceptScore W2022277266C71924100 @default.
• W2022277266 hasConceptScore W2022277266C85789140 @default.
• W2022277266 hasConceptScore W2022277266C86803240 @default.
• W2022277266 hasConceptScore W2022277266C95444343 @default.
• W2022277266 hasLocation W20222772661 @default.
• W2022277266 hasLocation W20222772662 @default.
• W2022277266 hasOpenAccess W2022277266 @default.
• W2022277266 hasPrimaryLocation W20222772661 @default.
• W2022277266 hasRelatedWork W1978578687 @default.

• next