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- W2022279957 abstract "Cancer in the paranasal sinuses and nasal cavities in a relatively rare tumor disease, with an annual incidence of about one case per 100,000 inhabitants in Europe and the United States.<sup>1</sup>The majority of these tumors start in the mucous membrane of the maxillary antrum or the ethmoid labyrinth. A few cases originate from the nasal cavities, while primary cancers in the sphenoid and frontal sinuses are extremely rare. The age-specific incidence of the disease continuously increases with age; it is predominately a disease of the middle aged and aging. The only known etiologic factor of some importance in antral carcinoma is chronic sinusitis. Long-standing sinusitis causes a squamous cell metaplasia of the respiratory epithelium, which probably is the origin of most antral cancers. Some patients have a long history with signs of chronic sinusitis, prior to the signs of progressive tumor. Squamous cell carcinoma is the most frequent" @default.
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- W2022279957 date "1972-01-17" @default.
- W2022279957 modified "2023-10-09" @default.
- W2022279957 title "Maxillary Antral Cancers" @default.
- W2022279957 doi "https://doi.org/10.1001/jama.1972.03190290036011" @default.
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