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- W2022280619 abstract "IT MAY be of interest to the reader of the Journal to discuss the management of a patient with primary amenorrhea over a period of seventeen years, during which time major developments in endocrinology have occurred. Miss S. B. (Fig. 1) was first seen in the metabolism clinic at the University of Chicago in April 1936, at the age of 18 years, complaining of failure to menstruate and a lack of normal breast development. She had been under medical care elsewhere for the preceding two years without beneficial results. The therapy consisted of dessicated thyroid and several endocrinal preparations of dubious potency. Her mother stated that her birth and early childhood were entirely uneventful. Scant pubic hair was noted at 11 years of age and a few axillary hairs a year later. However, growth of hair in these regions did not progress normally. Physical examination revealed a rather stocky young woman, 167 cm. tall, weighing 138 pounds and mentally alert. Her general appearance was that of a prepubertal child with the round face, the square shoulders, and the box-like hips characteristic of this undifferentiated period of development. The breasts were hardly discernible, the nipples were tiny and the areolae unpigmented." @default.
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- W2022280619 date "1953-12-01" @default.
- W2022280619 modified "2023-09-26" @default.
- W2022280619 title "PRIMARY OVARIAN FAILURE" @default.
- W2022280619 doi "https://doi.org/10.1210/jcem-13-12-1551" @default.
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