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- W2022281325 abstract "The present study was conducted to investigate genetic effects in cell mediated immunity in resistance to Marek's disease (MD), using the method of thymectomy and thymus transplantation. Chicks from the GVHR-HA and GVHR-LA lines selected for high and low competences in graft-versus-host reaction (GVHR) were thymectomized and some of them were mutually transplanted with the other line's thymus. The chicks were inoculated with the JV strain of MD virus. MD incidence and MD mortality were compared among three groups ; control, thymectomized and thymus transplanted. The HA line seemed to be more resistant to MD than the LA line. In the thymectomized groups, MD mortality increased in the HA line and decreased in the LA line. Mean days at MD incidence and MD death also showed the similar trend. In the thymus transplantation groups, significant increase in mortality was observed in the HA line which received thymus transplants from the LA line, while a non significant increase was also observed in the LA line received the HA thymus. Similar trend was also observed on the mean days at MD death. It was suggested that MD susceptibility might be transferred by thymus grafting." @default.
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- W2022281325 date "1991-01-01" @default.
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- W2022281325 title "Line Difference in Effects of Thymectomy and Thymus Transplantation on Marek's Disease Resistance in Chickens." @default.
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- W2022281325 doi "https://doi.org/10.2141/jpsa.28.300" @default.
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