Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022287711> ?p ?o ?g. }
- W2022287711 endingPage "1069" @default.
- W2022287711 startingPage "1061" @default.
- W2022287711 abstract "Nanoparticles possessing multiple functionalities provide synthetic handles for varied surface chemistries, making them useful for a range of applications such as biotargeting and drug delivery. However, the combination of interfering functionalities on the same particle is often challenging. We have employed a synthetic scheme involving chemical protection/deprotection to combine interfering functional groups on the same hydrogel nanoparticle. The synthesis of amine-containing poly(N-isopropylacrylamide) nanogels was carried out via free radical precipitation polymerization by incorporating a Fmoc-protected amine PEG macromonomer. The Fmoc group was then removed to obtain free amines, which were shown to be available for conjugation. We further explored pNIPAm-co-acrylic acid nanogels with a protected amine-PEG, yielding zwitterionic particles. With careful attention to the order of the chemoligation and deprotection steps, these interfering functional groups can be forced to behave in a pseudo-orthogonal fashion, allowing for multiple chemoligation steps that employ both the amine and carboxylic acid groups." @default.
- W2022287711 created "2016-06-24" @default.
- W2022287711 creator A5026148821 @default.
- W2022287711 creator A5043304452 @default.
- W2022287711 date "2008-06-01" @default.
- W2022287711 modified "2023-09-29" @default.
- W2022287711 title "Synthesis of multifunctional nanogels using a protected macromonomer approach" @default.
- W2022287711 cites W182860851 @default.
- W2022287711 cites W1969433804 @default.
- W2022287711 cites W1974043409 @default.
- W2022287711 cites W1982218431 @default.
- W2022287711 cites W1987753037 @default.
- W2022287711 cites W1992980485 @default.
- W2022287711 cites W1993326909 @default.
- W2022287711 cites W1996173073 @default.
- W2022287711 cites W2000978239 @default.
- W2022287711 cites W2001851575 @default.
- W2022287711 cites W2002661845 @default.
- W2022287711 cites W2003535886 @default.
- W2022287711 cites W2016445534 @default.
- W2022287711 cites W2017845692 @default.
- W2022287711 cites W2021626030 @default.
- W2022287711 cites W2026340057 @default.
- W2022287711 cites W2034671557 @default.
- W2022287711 cites W2035819916 @default.
- W2022287711 cites W2039197719 @default.
- W2022287711 cites W2049288477 @default.
- W2022287711 cites W2061363207 @default.
- W2022287711 cites W2062963580 @default.
- W2022287711 cites W20667322 @default.
- W2022287711 cites W2073678636 @default.
- W2022287711 cites W2078237468 @default.
- W2022287711 cites W2081730112 @default.
- W2022287711 cites W2082027989 @default.
- W2022287711 cites W2087874940 @default.
- W2022287711 cites W2093656442 @default.
- W2022287711 cites W2098507369 @default.
- W2022287711 cites W2100115360 @default.
- W2022287711 cites W2104630159 @default.
- W2022287711 cites W2106021160 @default.
- W2022287711 cites W2107125662 @default.
- W2022287711 cites W2112404993 @default.
- W2022287711 cites W2141564451 @default.
- W2022287711 cites W2150924986 @default.
- W2022287711 cites W2151482054 @default.
- W2022287711 cites W2162294498 @default.
- W2022287711 cites W2328522466 @default.
- W2022287711 cites W4233883507 @default.
- W2022287711 doi "https://doi.org/10.1007/s00396-008-1883-1" @default.
- W2022287711 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2600853" @default.
- W2022287711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19079744" @default.
- W2022287711 hasPublicationYear "2008" @default.
- W2022287711 type Work @default.
- W2022287711 sameAs 2022287711 @default.
- W2022287711 citedByCount "24" @default.
- W2022287711 countsByYear W20222877112012 @default.
- W2022287711 countsByYear W20222877112013 @default.
- W2022287711 countsByYear W20222877112014 @default.
- W2022287711 countsByYear W20222877112015 @default.
- W2022287711 countsByYear W20222877112016 @default.
- W2022287711 countsByYear W20222877112017 @default.
- W2022287711 countsByYear W20222877112020 @default.
- W2022287711 countsByYear W20222877112022 @default.
- W2022287711 countsByYear W20222877112023 @default.
- W2022287711 crossrefType "journal-article" @default.
- W2022287711 hasAuthorship W2022287711A5026148821 @default.
- W2022287711 hasAuthorship W2022287711A5043304452 @default.
- W2022287711 hasBestOaLocation W20222877112 @default.
- W2022287711 hasConcept C10138342 @default.
- W2022287711 hasConcept C111998727 @default.
- W2022287711 hasConcept C131779359 @default.
- W2022287711 hasConcept C136520611 @default.
- W2022287711 hasConcept C155672457 @default.
- W2022287711 hasConcept C15920480 @default.
- W2022287711 hasConcept C162324750 @default.
- W2022287711 hasConcept C171250308 @default.
- W2022287711 hasConcept C178790620 @default.
- W2022287711 hasConcept C185592680 @default.
- W2022287711 hasConcept C188027245 @default.
- W2022287711 hasConcept C192562407 @default.
- W2022287711 hasConcept C21951064 @default.
- W2022287711 hasConcept C2780503075 @default.
- W2022287711 hasConcept C44228677 @default.
- W2022287711 hasConcept C521977710 @default.
- W2022287711 hasConcept C54400483 @default.
- W2022287711 hasConceptScore W2022287711C10138342 @default.
- W2022287711 hasConceptScore W2022287711C111998727 @default.
- W2022287711 hasConceptScore W2022287711C131779359 @default.
- W2022287711 hasConceptScore W2022287711C136520611 @default.
- W2022287711 hasConceptScore W2022287711C155672457 @default.
- W2022287711 hasConceptScore W2022287711C15920480 @default.
- W2022287711 hasConceptScore W2022287711C162324750 @default.
- W2022287711 hasConceptScore W2022287711C171250308 @default.
- W2022287711 hasConceptScore W2022287711C178790620 @default.
- W2022287711 hasConceptScore W2022287711C185592680 @default.
- W2022287711 hasConceptScore W2022287711C188027245 @default.
- W2022287711 hasConceptScore W2022287711C192562407 @default.
- W2022287711 hasConceptScore W2022287711C21951064 @default.