FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2022289818> ?p ?o ?g. }

• W2022289818 endingPage "540" @default.
• W2022289818 startingPage "532" @default.
• W2022289818 abstract "Vertebrates share common mechanisms in the control of development and in the maintenance of neural and retinal function. The secreted factor Noggin, a BMP inhibitor, plays a crucial role in neural induction during embryonic development. Moreover, we have shown its involvement in retinal differentiation of pluripotent cells. Here we show Noggin expression in the adult retina in three vertebrate species. Four Noggin genes are present in zebrafish (Danio rerio; ZbNog1, 2, 3, 5), three in frog (Xenopus laevis; XenNog1, 2 and 4), and one in mouse (Mus musculus; mNog). Quantitative RT-PCR experiments show the presence of ZbNog3 and ZbNog5 mRNAs, but not ZbNog1 and ZbNog2, in the adult zebrafish retina. All three genes are expressed in the frog retina, and mNog in the mouse. Immunohistochemistry data show that Noggin proteins are predominantly localized in the Golgi apparatus of photoreceptors and in the fibers of the outer plexiform layer. Lower expression levels are also found in inner plexiform layer fibers, in ganglion cells, in the ciliary marginal zone, and in retinal pigmented epithelium. Our results show that Noggin has a specific cellular and sub-cellular expression in the adult vertebrate retina, which is conserved during evolution. In addition to its established role during embryonic development, we postulate that Noggin also exerts a functional role in the adult retina." @default.
• W2022289818 created "2016-06-24" @default.
• W2022289818 creator A5018911898 @default.
• W2022289818 creator A5057267397 @default.
• W2022289818 creator A5060309123 @default.
• W2022289818 creator A5061139829 @default.
• W2022289818 creator A5074599447 @default.
• W2022289818 date "2014-04-21" @default.
• W2022289818 modified "2023-09-29" @default.
• W2022289818 title "Noggin Expression in the Adult Retina Suggests a Conserved Role during Vertebrate Evolution" @default.
• W2022289818 cites W1919667732 @default.
• W2022289818 cites W1965012559 @default.
• W2022289818 cites W1978522370 @default.
• W2022289818 cites W1980817131 @default.
• W2022289818 cites W1984288177 @default.
• W2022289818 cites W1990938412 @default.
• W2022289818 cites W2005849699 @default.
• W2022289818 cites W2005943162 @default.
• W2022289818 cites W2011034991 @default.
• W2022289818 cites W2015160990 @default.
• W2022289818 cites W2016452081 @default.
• W2022289818 cites W2024279589 @default.
• W2022289818 cites W2033904138 @default.
• W2022289818 cites W2035900692 @default.
• W2022289818 cites W2047165320 @default.
• W2022289818 cites W2067696847 @default.
• W2022289818 cites W2079920065 @default.
• W2022289818 cites W2081339428 @default.
• W2022289818 cites W2084582407 @default.
• W2022289818 cites W2090288118 @default.
• W2022289818 cites W2091579099 @default.
• W2022289818 cites W2097556075 @default.
• W2022289818 cites W2114268866 @default.
• W2022289818 cites W2122146824 @default.
• W2022289818 cites W2130993929 @default.
• W2022289818 cites W2136283819 @default.
• W2022289818 cites W2140029604 @default.
• W2022289818 cites W2141538345 @default.
• W2022289818 cites W2161344343 @default.
• W2022289818 cites W4251897205 @default.
• W2022289818 doi "https://doi.org/10.1369/0022155414534691" @default.
• W2022289818 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4174622" @default.
• W2022289818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24752827" @default.
• W2022289818 hasPublicationYear "2014" @default.
• W2022289818 type Work @default.
• W2022289818 sameAs 2022289818 @default.
• W2022289818 citedByCount "8" @default.
• W2022289818 countsByYear W20222898182015 @default.
• W2022289818 countsByYear W20222898182016 @default.
• W2022289818 countsByYear W20222898182020 @default.
• W2022289818 countsByYear W20222898182021 @default.
• W2022289818 countsByYear W20222898182022 @default.
• W2022289818 countsByYear W20222898182023 @default.
• W2022289818 crossrefType "journal-article" @default.
• W2022289818 hasAuthorship W2022289818A5018911898 @default.
• W2022289818 hasAuthorship W2022289818A5057267397 @default.
• W2022289818 hasAuthorship W2022289818A5060309123 @default.
• W2022289818 hasAuthorship W2022289818A5061139829 @default.
• W2022289818 hasAuthorship W2022289818A5074599447 @default.
• W2022289818 hasBestOaLocation W20222898181 @default.
• W2022289818 hasConcept C104317684 @default.
• W2022289818 hasConcept C105702510 @default.
• W2022289818 hasConcept C145103041 @default.
• W2022289818 hasConcept C169760540 @default.
• W2022289818 hasConcept C177275483 @default.
• W2022289818 hasConcept C2776878037 @default.
• W2022289818 hasConcept C2777093970 @default.
• W2022289818 hasConcept C2777506830 @default.
• W2022289818 hasConcept C2777585161 @default.
• W2022289818 hasConcept C2778761762 @default.
• W2022289818 hasConcept C2779535977 @default.
• W2022289818 hasConcept C2780384893 @default.
• W2022289818 hasConcept C2780827179 @default.
• W2022289818 hasConcept C2781099447 @default.
• W2022289818 hasConcept C31507581 @default.
• W2022289818 hasConcept C54355233 @default.
• W2022289818 hasConcept C55493867 @default.
• W2022289818 hasConcept C86803240 @default.
• W2022289818 hasConcept C95444343 @default.
• W2022289818 hasConceptScore W2022289818C104317684 @default.
• W2022289818 hasConceptScore W2022289818C105702510 @default.
• W2022289818 hasConceptScore W2022289818C145103041 @default.
• W2022289818 hasConceptScore W2022289818C169760540 @default.
• W2022289818 hasConceptScore W2022289818C177275483 @default.
• W2022289818 hasConceptScore W2022289818C2776878037 @default.
• W2022289818 hasConceptScore W2022289818C2777093970 @default.
• W2022289818 hasConceptScore W2022289818C2777506830 @default.
• W2022289818 hasConceptScore W2022289818C2777585161 @default.
• W2022289818 hasConceptScore W2022289818C2778761762 @default.
• W2022289818 hasConceptScore W2022289818C2779535977 @default.
• W2022289818 hasConceptScore W2022289818C2780384893 @default.
• W2022289818 hasConceptScore W2022289818C2780827179 @default.
• W2022289818 hasConceptScore W2022289818C2781099447 @default.
• W2022289818 hasConceptScore W2022289818C31507581 @default.
• W2022289818 hasConceptScore W2022289818C54355233 @default.
• W2022289818 hasConceptScore W2022289818C55493867 @default.
• W2022289818 hasConceptScore W2022289818C86803240 @default.
• W2022289818 hasConceptScore W2022289818C95444343 @default.

• next